Evidence map›Paper›PMID 30460142›Full record

ArticleBiomedical optics express2018

Mapping the phase and amplitude of ossicular chain motion using sound-synchronous optical coherence vibrography.

Antoine Ramier, Jeffrey Tao Cheng, Michael E Ravicz, John J Rosowski, Seok-Hyun Yun

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  4. The effect of female hormone in otosclerosis. A comparative study and speculation about their effect on the ossicular chain based on the clinical results.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  5. Biomedical optics express · 2022
    Article
  6. Article
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  8. Article
  9. Mouse middle-ear forward and reverse acoustics.The Journal of the Acoustical Society of America · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Antoine RamierHarvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.
Jeffrey Tao ChengEaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Michael E RaviczEaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
John J RosowskiEaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Seok-Hyun YunHarvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.
Massachusetts Eye and Ear Infirmary · USMassachusetts General Hospital · US

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
STRUCTURE/FUNCTION RELATIONS IN MIDDLE EARSR01DC000194 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROSOWSKI, JOHN J · 1989 to 2018
$5.9M
NIBIB NIH HHS P41 EB015903NIDCD NIH HHS R01 DC000194
6 · The paper itself

Abstract

The sound-driven vibration of the tympanic membrane and ossicular chain of middle-ear bones is fundamental to hearing. Here we show that optical coherence tomography in phase synchrony with a sound stimulus is well suited for volumetric, vibrational imaging of the ossicles and tympanic membrane. This imaging tool - OCT vibrography - provides intuitive motion pictures of the ossicular chain and how they vary with frequency. Using the chinchilla ear as a model, we investigated the vibrational snapshots and phase delays of the manubrium, incus, and stapes over 100 Hz to 15 kHz. The vibrography images reveal a previously undescribed mode of motion of the chinchilla ossicles at high frequencies.

Identifiers

PMID30460142
PMCPMC6238908
OpenAlexW2897632623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.