Evidence map›Paper›PMID 30460119›Full record

ArticleBiomedical optics express2018

MEDnet, a neural network for automated detection of avascular area in OCT angiography.

Yukun Guo, Acner Camino, Jie Wang, David Huang, Thomas S Hwang, Yali Jia

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 96 citations in OpenAlex.

  1. Article
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  6. Nonperfused Retinal Capillaries-A New Method Developed on OCT and OCTA.Investigative ophthalmology & visual science · 2025
    Article
  7. Article
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  10. OCTA-based AMD Stage Grading Enhancement via Class-Conditioned Style Transfer.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
  11. Article
  12. Article
  13. Optical coherence tomography angiography in diabetic retinopathy.Progress in retinal and eye research · 2023
    Review
  14. Article
  15. Robust AMD Stage Grading with Exclusively OCTA Modality Leveraging 3D Volume.... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision · 2023
    Article
  16. Review
  17. Optical coherence tomography angiography: a review of the current literature.The Journal of international medical research · 2023
    Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yukun GuoCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Acner CaminoCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Jie WangCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
David HuangCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Thomas S HwangCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Yali JiaCasey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Oregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
Translational Vision Science Research at Oregon Health & Science UniversityT32EY023211 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Yali Jia, Kate E Keller · 2013 to 2026
$2.4M
Wide-field and projection-resolved optical coherence tomography angiography in diabetic retinopathyR01EY027833 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HWANG, THOMAS, JIA, YALI · 2017 to 2020
$1.8M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY024544NEI NIH HHS R01 EY027833NEI NIH HHS T32 EY023211NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

Screening and assessing diabetic retinopathy (DR) are essential for reducing morbidity associated with diabetes. Macular ischemia is known to correlate with the severity of retinopathy. Recent studies have shown that optical coherence tomography angiography (OCTA), with intrinsic contrast from blood flow motion, is well suited for quantified analysis of the avascular area, which is potentially a useful biomarker in DR. In this study, we propose the first deep learning solution to segment the avascular area in OCTA of DR. The network design consists of a multi-scaled encoder-decoder neural network (MEDnet) to detect the non-perfusion area in 6 × 6 mm

Identifiers

PMID30460119
PMCPMC6238913
OpenAlexW2895460990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.