Evidence map›Paper›PMID 30460118›Full record

ArticleBiomedical optics express2018

Speckle noise reduction in optical coherence tomography images based on edge-sensitive cGAN.

Yuhui Ma, Xinjian Chen, Weifang Zhu, Xuena Cheng, Dehui Xiang, Fei Shi

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Interferometric image denoising network SEVReNet.Biomedical optics express · 2026
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuhui MaSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.
Xinjian ChenSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.
Weifang ZhuSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.
Xuena ChengSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.
Dehui XiangSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.
Fei ShiSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Speckle noise in optical coherence tomography (OCT) impairs both the visual quality and the performance of automatic analysis. Edge preservation is an important issue for speckle reduction. In this paper, we propose an end-to-end framework for simultaneous speckle reduction and contrast enhancement for retinal OCT images based on the conditional generative adversarial network (cGAN). The edge loss function is added to the final objective so that the model is sensitive to the edge-related details. We also propose a novel method for obtaining clean images for training from outputs of commercial OCT scanners. The results show that the overall denoising performance of the proposed method is better than other traditional methods and deep learning methods. The proposed model also has good generalization ability and is capable of despeckling different types of retinal OCT images.

Identifiers

PMID30460118
PMCPMC6238896

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.