ArticleAnimal cells and systems2018
Characterization of changes of pain behavior and signal transduction system in food-deprived mice.
Article in Animal cells and systems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Six-month periodic fasting does not affect somatosensory nerve function in type 2 diabetes patients.Frontiers in endocrinology · 2023Trial
- Endogenous opioid receptors and the feast or famine of maladaptive feeding.Nature communications · 2025Review
- A Systematic Review of Dietary Lifestyle Interventions for Neuropathic Pain.Journal of clinical medicine · 2024Review
- Effects of Early Exposure to Isoflurane on Susceptibility to Chronic Pain Are Mediated by Increased Neural Activity Due to Actions of the Mammalian Target of the Rapamycin Pathway.International journal of molecular sciences · 2023Article
- Tropomyosin receptor kinase B-mediated signaling in integration of neuropathic pain and obesity in diabetic polyneuropathy.Einstein (Sao Paulo, Brazil) · 2021Article
- The analgesic effect of refeeding on acute and chronic inflammatory pain.Scientific reports · 2019Article
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Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fasting in general causes several metabolic changes. In the present study, we examined the possible changes of several types of nociception during the food deprivation were investigated in mice. After the mice were forced into the fasting for 12, 24, or 48 h, the changes of nociception were measured by the tail-flick, writhing, formalin or von-frey tests. We found that the nociceptive behavior induced by intraperitoneally (i.p.) administered acetic acid (writhing response) or intraplantar injection of 5% formalin into the hind-paw were reduced in fasted group. In addition, the tail-flick response and threshold for nociception in mechanical von-frey test were also elevated in fasted group. Moreover, the p-CREB and p-ERK levels in the dorsal root ganglia (DRG) and the spinal cord were reduced in food-deprived group. Furthermore, p-AMPKα
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Registered trials
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