Evidence map›Paper›PMID 30460064›Full record

ArticleAnimal cells and systems2017

Identification of molecular markers distinguishing adult neural stem cells in the subventricular and subcallosal zones.

Joo Yeon Kim, Mohammed R Shaker, Ju-Hyun Lee, Boram Lee, Hyun Kim, Woong Sun

Abstract read
In one paragraph

Article in Animal cells and systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joo Yeon KimDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.
Mohammed R ShakerDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.
Ju-Hyun LeeDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.
Boram LeeDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.
Hyun KimDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.
Woong SunDepartment of Anatomy, Korea University College of Medicine, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural stem cells (NSCs) in the adult subventricular zone (SVZ) are regionally specified and have distinct molecular gene expression signatures. Recently, we identified the subcallosal zone (SCZ) as a novel brain region where adult NSCs maintain and spontaneously produce neuroblasts. In an attempt to isolate genes specifically expressed in the SCZ or SVZ, microarray analyses of their differentially expressing transcripts were done. The comparison between neurospheres generated from SVZ and SCZ revealed differential expression >1.5-fold in two groups in only 83 genes, representing <0.03% of the genes examined, suggesting that these two populations are largely similar. The differential expression patterns SCZ and SVZ genes were confirmed by RT-PCR and Western blots. The selective expressions of two genes (

Indexed as

adult neural stem cellCRBP1HMGA1microarraysubcallosal zoneSubventricular zoneZIC2

Identifiers

PMID30460064
PMCPMC6138335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.