ArticleCanine genetics and epidemiology2018
Neuter status as a risk factor for canine intervertebral disc herniation (IVDH) in dachshunds: a retrospective cohort study.
Article in Canine genetics and epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- When - and whether - should we spay/neuter companion dogs.The Journal of small animal practice · 2025Review
- Allelic frequency of 12-FGF4RG and the association between the genotype with number of calcified intervertebral discs visible on radiographs in Coton de Tuléar and French Bulldog breeds.BMC veterinary research · 2025Article
- Comparison of Clinical Features of Intervertebral Disc Extrusions in English Cocker Spaniels, French Bulldogs and Dachshunds.Animals : an open access journal from MDPI · 2025Article
- Influence of gonadectomy and age at gonadectomy on the risk of developing intervertebral disc herniation in French Bulldogs: a retrospective study.Frontiers in veterinary science · 2025Article
- Cross-sectional survey of 43,517 dogs in the Dog Aging Project identifies owner-reported lifetime prevalence and characteristics of gastrointestinal disease.Journal of the American Veterinary Medical Association · 2024Article
- Epidemiology of CanineAnimals : an open access journal from MDPI · 2024Article
- Clinical presentation, magnetic resonance imaging findings, and outcome of 80 Dachshunds with cervical intervertebral disc extrusion.Frontiers in veterinary science · 2024Article
- Evaluation of intervertebral disc degeneration in young adult asymptomatic Dachshunds with magnetic resonance imaging and radiography.Acta veterinaria Scandinavica · 2023Article
- Prevalence, clinical presentation and MRI of intervertebral disc herniations in cats.Journal of feline medicine and surgery · 2022Article
- Breeding schemes for intervertebral disc disease in dachshunds: Is disc calcification score preferable to genotyping of the FGF4 retrogene insertion on CFA12?Canine medicine and genetics · 2020Article
- Colder Ambient Temperatures Influence Acute Onset Canine Intervertebral Disc Extrusion.Frontiers in veterinary science · 2020Article
- Current Understanding of the Genetics of Intervertebral Disc Degeneration.Frontiers in veterinary science · 2020Review
- Assisting Decision-Making on Age of Neutering for 35 Breeds of Dogs: Associated Joint Disorders, Cancers, and Urinary Incontinence.Frontiers in veterinary science · 2020Article
- A Review of the Impact of Neuter Status on Expression of Inherited Conditions in Dogs.Frontiers in veterinary science · 2019Review
- Outcomes of surgically and conservatively managed thoracolumbar and lumbosacral intervertebral disc herniations in cats.Journal of veterinary internal medicineArticle
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntervertebral disc herniation (IVDH) involves displacement of the intervertebral disc secondary to disc degeneration and is extremely common in dachshunds. Clinical signs include pain with or without paresis or paralysis. Mortality rate is high and some cases are left with permanent disability even after treatment. Aims of this study were twofold: Firstly, to investigate whether neutering, i.e. gonadectomy, is associated with increased risk of IVDH in dachshunds, and secondly to investigate whether age of neutering alters risk of IVDH in this breed.Information was obtained for 1964 dachshunds from the owner survey, "Dachslife 2015". For dachshunds that were ≥ 3 years and < 10 years old at the time of the survey (1073 individuals) incidence of IVDH was compared between early-neutered (< 12 months), late-neutered (> 12 months) and entire animals of each gender.
resultsNeutered females were at significantly higher risk of IVDH than entire females (risk ratio 1.81, 95% CI 1.28-2.54). For males, incidence of IVDH in neutered as compared with entire dachshunds was increased but this difference was not quite statistically significant (risk ratio 1.38, 95% CI 0.96-1.99).For both genders, this study demonstrated significantly increased risk of IVDH in early-neutered dachshunds (before 12 months old) as compared with those neutered late (after 12 months old). For early neutered males, risk ratio was 1.54 (95% CI 1.07-2.22). For early-neutered females, risk ratio was 2.12 (95% CI 1.44-3.11).
conclusionResults from this retrospective study suggest that gonadectomy, especially if performed before 12 months old, increases risk of IVDH in this breed. Decisions regarding neutering should be made on an individual basis, taking a range of pros and cons into account. Considering the high prevalence, morbidity and mortality of IVDH in dachshunds, increased IVDH risk associated with neutering is a key factor to consider in deciding whether and when to neuter.
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