ArticleBMC hematology2018
A ten year review of the sickle cell program in Muhimbili National Hospital, Tanzania.
Article in BMC hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Pooled it
- Prevalence and Determinants of Chronic Kidney Disease among Patients with Sickle Cell Disease in Tanzania.Research square · 2026Article
- Factors Affecting Pain Control in Patients with Sickle Cell Disease at Mwananyamala and Muhimbili Hospitals in Dar es Salaam, Tanzania.Journal of clinical medicine · 2026Article
- Mapping the Research Growth and Citation Impact of Scholarly Works on Sickle Cell Disease in Tanzania: A Scientometric Study.BioMed research international · 2026Article
- Building a Comprehensive Sickle Cell Disease Program in Western Kenya: A Decade of Experience and Growth.Annals of global health · 2026Article
- "I Know that One Day I Will Be Cured": Perspectives on Acceptability of Curative Therapies for Sickle Cell Disease in Tanzania.Public health genomics · 2026Article
- Early-life clinical and hematological profiles: a comparative study of children with and without sickle cell disease in the first three years of life.Annals of hematology · 2025Article
- Lived Experiences of Clinical Depression Among Adolescents With Sickle Cell Anemia in Dar-es-salaam, Tanzania: A Qualitative Study.Research square · 2025Article
- Integrating sickle cell disease care into primary healthcare in Uganda: a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Preventive interventions and diagnostic testing compliance in the management of tropical infections among patients with sickle cell disease in Tanzania.Parasites, hosts and diseases · 2025Observational
- Adherence to Hydroxyurea Therapy for Pediatric Sickle Cell Anemia in Tanzania: Evidence from Bugando Medical Centre.International journal of environmental research and public health · 2025Article
- Assessment of healthcare workers' knowledge and availability of resources for sickle cell disease management in Bukavu, Democratic Republic of the Congo.BMC health services research · 2025Article
- Strengthening advanced therapy for sickle cell disease in Africa: experience from sickle cell disease centre in Dar es Salaam, Tanzania.BMJ global health · 2025Article
- Clinical depression prevalence and associated factors among adolescents with sickle cell anemia in dar es salaam, tanzania: a cross-sectional study.BMC pediatrics · 2025Article
- Utilization of Fetal Hemoglobin Parameters in Predicting Clinical Severity of Sickle Cell Disease: Retrospective Study From a Tanzanian Cohort.Journal of blood medicine · 2025Article
- High Prevalence of Sickle Cell Disease in Low-Endemic Areas: A Pilot Study in Chunya Tanzania.The East African health research journal · 2025Article
- Globalization in clinical drug development for sickle cell disease.American journal of hematology · 2025Article
- Improved Biorepository to Support Sickle Cell Disease Genomics and Clinical Research: A Practical Approach to Link Patient Data and Biospecimens from Muhimbili Sickle Cell Program, Tanzania.Biopreservation and biobanking · 2024Article
- Prevalence and predictors of iron deficiency anaemia among children with sickle cell disease in Dodoma, Tanzania: a cross-sectional study.BMC public health · 2024Article
- Article
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 4 countries.
Funding
Abstract
backgroundAfrica has the highest burden of Sickle cell disease (SCD) but there are few large, systematic studies providing reliable descriptions of the disease spectrum. Tanzania, with 11,000 SCD births annually, established the Muhimbili Sickle Cell program aiming to improve understanding of SCD in Africa. We report the profile of SCD seen in the first 10 years at Muhimbili National Hospital (MNH).
methodsIndividuals seen at MNH known or suspected to have SCD were enrolled at clinic and laboratory testing for SCD, haematological and biochemical analyses done. Ethnicity was self-reported. Clinical and laboratory features of SCD were documented. Comparison was made with non-SCD population as well as within 3 different age groups (< 5, 5-17 and ≥ 18 years) within the SCD population.
resultsFrom 2004 to 2013, 6397 individuals, 3751 (58.6%) SCD patients, were enrolled, the majority (47.4%) in age group 5-17 years. There was variation in the geographical distribution of SCD. Individuals with SCD compared to non-SCD, had significantly lower blood pressure and peripheral oxygen saturation (SpO
conclusionThis report confirms that the wide spectrum of clinical expression of SCD observed elsewhere is also present in Tanzania, with non-uniform geographical distribution across the country. Age-specific analysis is consistent with different disease-patterns across the lifespan.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.