Evidence map›Paper›PMID 30459951›Full record

ArticlePharmacology research & perspectives2018

The role of loops B and C in determining the potentiation of GABA

Olivia A Moody, Andrew Jenkins

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. The role of loops B and C in determining the potentiation of GABAPharmacology research & perspectives · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Olivia A MoodyNeuroscience Program Graduate Division of Biological and Biomedical Sciences Laney Graduate School Emory University Atlanta Georgia.
Andrew JenkinsDepartments of Anesthesiology & Pharmacology Emory University Atlanta Georgia.ORCID 0000-0003-3874-0795
Emory University · US

Funding

Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
TRAINING IN TRANSLATIONAL RESEARCH IN NEUROLOGYT32NS007480 · NINDS · EMORY UNIVERSITY · PI LEVEY, ALLAN I · 2000 to 2020
$4.5M
Characterization of an endogenous GABA-ergic mechanism underlying hypersomniaR01NS089719 · NINDS · EMORY UNIVERSITY · PI RYE, DAVID B · 2015 to 2018
$2.4M
NIGMS NIH HHS T32 GM008602NINDS NIH HHS R01 NS089719NINDS NIH HHS T32 NS007480
6 · The paper itself

Abstract

Many benzodiazepines are positive allosteric modulators (PAMs) of GABA

Indexed as

Allosteric RegulationAllosteric SiteGABA ModulatorsHEK293 CellsHumansMidazolamMutagenesis, Site-DirectedPatch-Clamp TechniquesProtein Structure, SecondaryReceptors, GABA-ASerineThreonineGABA ModulatorsMidazolamReceptors, GABA-ASerineThreonineallosteric modulatorbenzodiazepinecanonical loopsGABA(A) receptor

Identifiers

PMID30459951
PMCPMC6234229
OpenAlexW2901014514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.