Evidence map›Paper›PMID 30459864›Full record

ArticleAsian journal of neurosurgery

Controlled Trial to Compare Therapeutic Efficacy of Endoscopic Third Ventriculostomy Plus Choroid Plexus Cauterization with Ventriculoperitoneal Shunt in Infants with Obstructive Hydrocephalus.

Amir Amini Navaei, Sara Hanaei, Zohreh Habibi, Morteza Faghih Jouibari, Vahid Heidari, Soheil Naderi, Farideh Nejat

Open access · hybridAbstract read
In one paragraph

Article in Asian journal of neurosurgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amir Amini NavaeiDepartment of Neurosurgery, Shariati Hospital, Tehran University of Medical Science, Tehran, Iran.
Sara HanaeiDepartment of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
Zohreh HabibiDepartment of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
Morteza Faghih JouibariDepartment of Neurosurgery, Shariati Hospital, Tehran University of Medical Science, Tehran, Iran.
Vahid HeidariDepartment of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
Soheil NaderiDepartment of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
Farideh NejatDepartment of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Tehran, Iran.
University of Tehran · IRShariati Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextVentriculoperitoneal (VP) shunt and endoscopic third ventriculostomy (ETV) are the established surgical treatments for obstructive hydrocephalus (HCP). Powerful evidence regarding the best therapeutic approach for infants with obstructive HCP is lacked.

aimsComparison of the therapeutic efficacy of VP shunt and ETV/choroid plexus cauterization (CPC) in infants with obstructive HCP. SETTINGS AND

designThis was a randomized, active control, unblind, single-center, clinical trial.

methodsInfants with obstructive HCP were randomly allocated to each intervention group (ETV/CPC or VP shunt). They were monitored for at least 6 months for any sign of raised intracranial pressure (rICP). The recurrence of rICP signs requiring surgical intervention was considered as intervention failure. STATISTICAL ANALYSIS: The association between intervention group and outcome was tested with Chi-square test, and

resultsOf the total fifty patients entering the study, 49 were included in the final analysis, 27 of them were in VP shunt and 22 in ETV/CPC group. Seventeen patients (34%) were female and 33 (66%) were male with mean age of 3.74 ± 3.1 months (range = 10 days - 11 months). Thirty-nine (79.6%) were under 6 months of age and the remaining were 6 months or older. The overall success rate in 36-month follow-up was 88.5% and 68.2% for VP shunt and ETV/CPC, respectively, with the difference being not statistically significant.

conclusionThe current study determined no inferiority of ETV/CPC compared to VP shunt, and therefore, it may become an efficient treatment for obstructive HCP in infants.

Indexed as

Endoscopic third ventriculostomyhydrocephalussuccessventriculoperitoneal shunt

Identifiers

PMID30459864
PMCPMC6208245
OpenAlexW2800928316

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.