ReviewAsian journal of neurosurgery
A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations.
Review in Asian journal of neurosurgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
74 citing papers in PubMed, 146 citations in OpenAlex.
- Nerve-rattling infections! Clinical and radiological tracing of cranial nerve palsies to infectious skull base osteomyelitis.Indian journal of ophthalmology · 2026Observational
- Clinical Features and Surgical Outcomes in Patients With Central Skull Base Osteomyelitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Atypical Skull Base Osteomyelitis of the Clivus Mimicking a Malignant Lesion: A Case Report.Diseases (Basel, Switzerland) · 2026Article
- Optimizing skull base osteomyelitis treatment: effectiveness of antibiotic therapy within a multimodal approach.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Malignant Otitis Externa Complicated by Skull Base Osteomyelitis Presenting as Vernet's Syndrome with Central Venous Thrombosis.Asian journal of neurosurgery · 2026Article
- A prospective multicentric study of microbiological profile, treatment protocols and clinical indicators of cure in skull base osteomyelitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Observational
- Article
- CT-negative central skull base osteomyelitis diagnosed on MRI in the emergency department.BMJ case reports · 2025Article
- Review
- Clinical Features and Outcomes of Chronic Otitis Media Complications: A 20-Year Retrospective Study at a Tertiary Hospital.World journal of otorhinolaryngology - head and neck surgery · 2025Article
- Article
- Skull Base Osteomyelitis- Microbiological Profile and Management Implications.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review.Journal of neurological surgery. Part B, Skull base · 2025Review
- A pathogen-detection's odyssey in a case of skull base osteomyelitis: Land ahoy!Annals of clinical microbiology and antimicrobials · 2025Article
- Malignant Fungating Wounds in Locally Aggressive Cutaneous Squamous Cell Carcinoma: A Case Series.Cureus · 2025Article
- Understanding the Impact of Skull Base Osteomyelitis: A Retrospective Analysis of 14 Cases.Cureus · 2025Article
- Foreign Contaminants Target Brain Health.CNS & neurological disorders drug targets · 2025Review
- Skull Base Osteomyelitis and Parapharyngeal Abscess as Complications of Otitis Media in a Young Immunocompetent Man.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Central Skull Base Osteomyelitis in Queensland, Australia, 2010-2020.Open forum infectious diseases · 2024Article
- Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic, sinogenic, odontogenic, and rhinogenic infections and can present as central, atypical, or pediatric clival SBO. This review describes the clinical profile, investigational approach, and management techniques for these variants. A comprehensive literature review was performed in PubMed, MEDLINE, Research Gate, EMBASE, Wiley Online Library, and various Neurosurgical and Neurology journals with the keywords including: SBO, central or atypical SBO, fungal osteomyelitis, malignant otitis externa, temporal bone osteomyelitis, and clival osteomyelitis. Each manuscript's reference list was reviewed for potentially relevant articles. The search yielded a total of 153 articles. It was found that with early and aggressive culture guided long-term intravenous broad-spectrum antibiotic therapy decreases post-infection complications. In cases of widespread soft tissue involvement, an early aggressive surgical removal of infectious sequestra with preferentially Hyperbaric Oxygen (HBO) therapy is associated with better prognosis of disease, less neurologic sequelae and mortality rate. Complete resolution of the SBO cases may take several months. Since early treatment can improve mortality rates, it is paramount that the reporting radiologists and treating clinicians are aware of the cardinal diagnostic signs to improve clinical outcomes of the disease. It will decrease delayed diagnosis and under treatment of the condition. However, due to rarity of the condition, complete prognostic factors have not fully been analyzed and discussed in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.