Evidence map›Paper›PMID 30459807›Full record

ArticleFrontiers in genetics2018

Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the

Robert Durruthy-Durruthy, Ethan D Sperry, Margot E Bowen, Laura D Attardi, Stefan Heller, Donna M Martin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. CHD7 and SOX2 act in a common gene regulatory network during mammalian semicircular canal and cochlear development.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Single-Cell Sequencing Applications in the Inner Ear.Frontiers in cell and developmental biology · 2021
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robert Durruthy-DurruthyDepartments of Otolaryngology - Head and Neck Surgery, Stanford University, Stanford, CA, United States.
Ethan D SperryMedical Scientist Training Program, University of Michigan, Ann Arbor, MI, United States.
Margot E BowenDivision of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, CA, United States.
Laura D AttardiDivision of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, CA, United States.
Stefan HellerDepartments of Otolaryngology - Head and Neck Surgery, Stanford University, Stanford, CA, United States.
Donna M MartinMedical Scientist Training Program, University of Michigan, Ann Arbor, MI, United States.
Stanford University · USUniversity of Michigan–Ann Arbor · US

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Developmental Mechanisms of the Chromodomain Gene Chd7R01DC009410 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARTIN, DONNA M. · 2009 to 2018
$3.7M
Exploration of Connexin26 Genotypes, Phenotypes, and Gene ReplacementR01DC014456 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARTIN, DONNA M., RAPHAEL, YEHOASH · 2016 to 2020
$2.5M
NIDCD NIH HHS R01 DC009410NIDCD NIH HHS R01 DC014456NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

The chromatin remodeling protein CHD7 is critical for proper formation of the mammalian inner ear. Humans with heterozygous pathogenic variants in

Indexed as

CHARGE syndromeCHD7chromatin remodelinginner ear developmentmouse modelsotic vesiclepatterningsingle cell genomics

Identifiers

PMID30459807
PMCPMC6232929
OpenAlexW2896013409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.