Evidence map›Paper›PMID 30459773›Full record

ArticleFrontiers in immunology2018

The Role of BACH2 in T Cells in Experimental Malaria Caused by

Chelsea L Edwards, Marcela Montes de Oca, Fabian de Labastida Rivera, Rajiv Kumar, Susanna S Ng, Yulin Wang, Fiona H Amante, Kohei Kometani, Tomohiro Kurosaki, Tom Sidwell and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Chelsea L EdwardsQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Marcela Montes de OcaQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Fabian de Labastida RiveraQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Rajiv KumarDepartment of Biochemistry, Banaras Hindu University, Varanasi, India.
Susanna S NgQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Yulin WangQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Fiona H AmanteQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Kohei KometaniLaboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan.
Tomohiro KurosakiLaboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Tom SidwellDepartment of Microbiology and Immunology, The Peter Doherty Institute of Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Axel KalliesDepartment of Microbiology and Immunology, The Peter Doherty Institute of Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Christian R EngwerdaQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
QIMR Berghofer Medical Research Institute · AUBanaras Hindu University · INGriffith University · AUOsaka University · JPRIKEN Center for Integrative Medical Sciences · JPUniversity of Melbourne · AUUniversity of Queensland · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2) is a transcription factor best known for its role in B cell development. More recently, it has been associated with T cell functions in inflammatory diseases, and has been proposed as a master transcriptional regulator within the T cell compartment. In this study, we employed T cell-specific

Indexed as

AnimalsBasic-Leucine Zipper Transcription FactorsCell DifferentiationCell ProliferationCells, CulturedChimeraFemaleHumansLymphocyte ActivationMalariaMiceMice, Inbred C57BLMice, KnockoutModels, AnimalPlasmodium chabaudiTh17 CellsBach2 protein, mouseBasic-Leucine Zipper Transcription FactorsBACH2inflammationmalariaprotozoanT cells

Identifiers

PMID30459773
PMCPMC6232374
OpenAlexW2898573786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.