Evidence map›Paper›PMID 30459590›Full record

ArticleFrontiers in synaptic neuroscience2018

Emergence of Endocytosis-Dependent mGlu1 LTD at Nucleus Accumbens Synapses After Withdrawal From Cocaine Self-Administration.

Andrew F Scheyer, Daniel T Christian, Marina E Wolf, Kuei Y Tseng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Positive Allosteric Modulation of mGluBiological psychiatry · 2022
    Article
  4. FACTORS CONTRIBUTING TO THE ESCALATION OF ALCOHOL CONSUMPTION.Neuroscience and biobehavioral reviews · 2022
    Review
  5. Article
  6. CaThe Journal of physiology · 2021
    Article
  7. Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew F ScheyerDepartment of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.
Daniel T ChristianDepartment of Neuroscience, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.
Marina E WolfDepartment of Neuroscience, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.
Kuei Y TsengDepartment of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.
Rosalind Franklin University of Medicine and Science · US

Funding

Reversal of AMPA receptor plasticity underlying incubation of cocaine cravingR01DA009621 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE &SCI · PI Marina Elizabeth Wolf · 1996 to 2026
$8.5M
Dopamine and Glutamate Receptor InteractionsR37DA015835 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE &SCI · PI WOLF, MARINA ELIZABETH · 2003 to 2012
$2.8M
Synaptic mechanisms maintaining persistent cocaine craving.R01DA015835 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI WOLF, MARINA ELIZABETH · 2014 to 2018
$1.8M
Plasticity in nucleus accumbens spines during incubation of cocaine cravingF32DA036963 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI CHRISTIAN, DANIEL TOMMIS · 2014 to 2017
$159k
Synaptic adaptations underlying the incubation of cocaine cravingF31DA036327 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI SCHEYER, ANDREW FORD · 2013 to 2015
$101k
NIDA NIH HHS F31 DA036327NIDA NIH HHS F32 DA036963NIDA NIH HHS R01 DA009621NIDA NIH HHS R01 DA015835NIDA NIH HHS R37 DA015835
6 · The paper itself

Abstract

Extended-access cocaine self-administration induces a progressive intensification of cue-induced drug craving during withdrawal termed "incubation of cocaine craving". Rats evaluated after >1 month of withdrawal (when incubation of craving is robust) display alterations in excitatory synapses onto medium spiny neurons (MSNs) of the nucleus accumbens (NAc), including elevated levels of Ca

Indexed as

calcium-permeable AMPA receptorcocaine withdrawallong-term depressionmetabotropic glutamate receptor 1nucleus accumbenssynaptic transmission

Identifiers

PMID30459590
PMCPMC6232902
OpenAlexW2897921578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.