ArticleFrontiers in human neuroscience2018
Diffusion Tensor Imaging Detects Microstructural Differences of Visual Pathway in Patients With Primary Open-Angle Glaucoma and Ocular Hypertension.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Unveiling Novel Structural Biomarkers for the Diagnosis of Glaucoma.Biomedicines · 2024Review
- Diffusion tensor imaging of optic neuropathies: a narrative review.Quantitative imaging in medicine and surgery · 2024Review
- Correlation between retinal structure and brain multimodal magnetic resonance imaging in patients with Alzheimer's disease.Frontiers in aging neuroscience · 2023Article
- Magnetic resonance imaging assessment of the lateral geniculate nucleus volume and height in patients with glaucoma: a Meta-analysis.International journal of ophthalmology · 2023Article
- Application of diffusion tensor imaging technology in glaucoma diagnosis.Frontiers in neuroscience · 2023Review
- Microstructural Visual Pathway White Matter Alterations in Primary Open-Angle Glaucoma: A Neurite Orientation Dispersion and Density Imaging Study.AJNR. American journal of neuroradiology · 2022Article
- Advanced Diffusion MRI of the Visual System in Glaucoma: From Experimental Animal Models to Humans.Biology · 2022Review
- Multi-Contrast Magnetic Resonance Imaging of Visual White Matter Pathways in Patients With Glaucoma.Investigative ophthalmology & visual science · 2022Article
- Multi-Parametric Diffusion Tensor Imaging of The Optic Nerve for Detection of Dysthyroid Optic Neuropathy in Patients With Thyroid-Associated Ophthalmopathy.Frontiers in endocrinology · 2022Article
- The Causal Association Between Obesity and Primary Open-Angle Glaucoma: A Two-Sample Mendelian Randomization Study.Frontiers in genetics · 2022Article
- Thyroid-associated ophthalmopathy: Using diffusion tensor imaging to evaluate visual pathway microstructural changes.Frontiers in neurology · 2022Article
- Transneuronal Degeneration in the Brain During Glaucoma.Frontiers in aging neuroscience · 2021Review
- Progression of Visual Pathway Degeneration in Primary Open-Angle Glaucoma: A Longitudinal Study.Frontiers in human neuroscience · 2021Article
- Reorganization of the structural connectome in primary open angle Glaucoma.NeuroImage. Clinical · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ocular hypertension (OHT), the common situation in adult patients in the outpatients, occurs ∼5% worldwide. However, there are still some practical problems in differentiation of OHT with early primary open-angle glaucoma (POAG) using current standard methods. Application of high resolution diffusion tensor imaging (DTI) enables us to the differentiate axonal architecture of visual pathway between POAG and OHT subjects. Among 32 POAG patients recruited (15 OHT and 14 control subjects), 62.5% of glaucoma were in early stage for the current study. All subjects underwent ophthalmological assessments with standard automated perimetry and optical coherence tomography (OCT). DTI was applied to measure fraction anisotropy (FA) and mean diffusivity (MD) of optic tract (OT), lateral geniculate body (LGN) and optic radiation (OR) using voxel-based analysis. Our data demonstrated that FA values of bilateral OR in POAG were significantly lower in the right or left than that of OHT patients (left OR: 0.51 ± 0.04 vs. 0.54 ± 0.03,
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