Evidence map›Paper›PMID 30459320›Full record

ArticleScientific reports2018

Decreased microbial co-occurrence network stability and SCFA receptor level correlates with obesity in African-origin women.

Lara R Dugas, Beatriz Peñalver Bernabé, Medha Priyadarshini, Na Fei, Seo Jin Park, Laquita Brown, Jacob Plange-Rhule, David Nelson, Evelyn C Toh, Xiang Gao and 7 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Lara R DugasPublic Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA. ldugas@luc.edu.ORCID http://orcid.org/0000-0002-0692-8585
Beatriz Peñalver BernabéMicrobiome Center, Department of Surgery, University of Chicago, Chicago, IL, USA.
Medha PriyadarshiniDivision of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-2972-2528
Na FeiMicrobiome Center, Department of Surgery, University of Chicago, Chicago, IL, USA.
Seo Jin ParkDepartment of Microbiology-Immunology, Northwestern University, Chicago, Illinois, USA.
Laquita BrownPublic Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Jacob Plange-RhuleKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
David NelsonDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, USA.
Evelyn C TohDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, USA.
Xiang GaoPublic Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Qunfeng DongPublic Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Jun SunDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0001-7465-3133
Stephanie KliethermesDepartment of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Wisconsin, USA.
Neil GottelMicrobiome Center, Department of Surgery, University of Chicago, Chicago, IL, USA.
Amy LukePublic Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Jack A GilbertMicrobiome Center, Department of Surgery, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7920-7001
Brian T LaydenDivision of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago, Chicago, IL, USA.
Loyola University Chicago · USUniversity of Chicago · USUniversity of Illinois Chicago · USIndiana University School of MedicineKwame Nkrumah University of Science and Technology · GHNorthwestern University · USUniversity of Wisconsin–Madison · US

Funding

The function and regulation of the novel pregnancy-specific hexokinase HKDC1R01DK104927 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAYDEN, BRIAN THOMAS, REDDY, TIMOTHY E · 2015 to 2024
$7.2M
Determinants and Consequences of Low Vitamin D in Populations of African DescentR01DK090360 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI DURAZO-ARVIZU, RAMON ANGEL · 2011 to 2015
$3.0M
Gut microbiota, short chain fatty acids, and adiposity across the epidemiologic transitionR01DK111848 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI DUGAS, LARA RUTH · 2017 to 2021
$3.0M
Modeling the epidemiologic transition: Energy expenditure, obesity and diabetesR01DK080763 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI LUKE, AMY H · 2009 to 2012
$2.4M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
Role of Nutrient Sensing Receptors for the Gut Microbiota in MetabolismI01BX003382 · VA · JESSE BROWN VA MEDICAL CENTER · PI LAYDEN, BRIAN THOMAS · 2017 to 2025
–
BLRD VA I01 BX003382NIDDK NIH HHS R01 DK080763NIDDK NIH HHS R01 DK090360NIDDK NIH HHS R01 DK104927NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK111848U.S. Department of Health & Human Services | National Institutes of Health (NIH) 080763U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01-DK080763U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01-Dk104927U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01-DK111848U.S. Department of Veterans Affairs (VA) 1I01BX003382
6 · The paper itself

Abstract

We compared the gut microbial populations in 100 women, from rural Ghana and urban US [50% lean (BMI < 25 kg/m

Indexed as

Feeding BehaviorAdiposityAdultBlack or African AmericanBody Mass IndexDiet, High-FatFatty Acids, VolatileFecal Microbiota TransplantationFemaleGastrointestinal MicrobiomeGhanaHumansObesityReceptors, Cell SurfaceReceptors, G-Protein-CoupledSouth AfricaFatty Acids, VolatileFfar2 protein, mouseFFAR3 protein, mouseReceptors, Cell SurfaceReceptors, G-Protein-Coupled

Identifiers

PMID30459320
PMCPMC6244201
OpenAlexW2901911160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.