Evidence map›Paper›PMID 30459265›Full record

ArticlePlant physiology2019

The Largest Subunit of DNA Polymerase Delta Is Required for Normal Formation of Meiotic Type I Crossovers.

Cong Wang, Jiyue Huang, Jun Zhang, Hongkuan Wang, Yapeng Han, Gregory P Copenhaver, Hong Ma, Yingxiang Wang

Open access · greenAbstract read
In one paragraph

Article in Plant physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. SCFNature communications · 2023
    Article
  4. Article
  5. Crossover interference mechanism: New lessons from plants.Frontiers in cell and developmental biology · 2023
    Review
  6. DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Comparison of Metabolic Profiling ofPhenomics (Cham, Switzerland) · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Plant DNA Polymerases.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Cong WangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-1647-1072
Jiyue HuangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-7185-4201
Jun ZhangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-9070-8701
Hongkuan WangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.
Yapeng HanState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.
Gregory P CopenhaverDepartment of Biology and Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599-3280.ORCID 0000-0002-7962-3862
Hong MaState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0001-8717-4422
Yingxiang WangState Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China yx_wang@fudan.edu.cn.ORCID 0000-0001-6085-5615
Fudan University · CNUniversity of North Carolina at Chapel Hill · USPennsylvania State University · USXinyang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meiotic recombination contributes to the maintenance of the association between homologous chromosomes (homologs) and ensures the accurate segregation of homologs during anaphase I, thus facilitating the redistribution of alleles among progeny. Meiotic recombination is initiated by the programmed formation of DNA double strand breaks, the repair of which requires DNA synthesis, but the role of DNA synthesis proteins during meiosis is largely unknown. Here, we hypothesized that the lagging strand-specific DNA Polymerase δ (POL δ) might be required for meiotic recombination, based on a previous analysis of DNA Replication Factor1 that suggested a role for lagging strand synthesis in meiotic recombination. In Arabidopsis (

Indexed as

Crossing Over, GeneticArabidopsisArabidopsis ProteinsChromosome PairingDNA Breaks, Double-StrandedDNA Polymerase IIIDNA RepairFertilityGene Knockdown TechniquesHomologous RecombinationMeiosisPlants, Genetically ModifiedProtein SubunitsArabidopsis ProteinsAT5G63960 protein, ArabidopsisDNA Polymerase IIIPOLD2 protein, ArabidopsisProtein Subunits

Identifiers

PMID30459265
PMCPMC6426404
OpenAlexW2901640127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.