Evidence map›Paper›PMID 30459262›Full record

ArticleThe Journal of cell biology2019

Cell-cycle control of cell polarity in yeast.

Kyle D Moran, Hui Kang, Ana V Araujo, Trevin R Zyla, Koji Saito, Denis Tsygankov, Daniel J Lew

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Polarization as a Process: The Potential of Process Ontology for Understanding Cellular Symmetry Breaking.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Roles for the canonical polarity machinery in thebioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Mechanism of commitment to a mating partner inMolecular biology of the cell · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kyle D MoranDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC.ORCID 0000-0001-8824-1463
Hui KangDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC.
Ana V AraujoDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC.
Trevin R ZylaDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC.
Koji SaitoDepartment of Biosciences, School of Science, Kitasato University, Kitasato, Sagamihara, Kanagawa, Japan.
Denis TsygankovWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-1180-3584
Daniel J LewDepartment of Pharmacology and Cancer Biology, Duke University, Durham, NC daniel.lew@duke.edu.ORCID 0000-0001-7482-3585
Duke University · USGeorgia Institute of Technology · USKitasato University · JP

Funding

Studies on cell polarity, chemotropism, and cell cycle controlR35GM122488 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DANIEL J LEW · 2017 to 2026
$6.9M
POLARITY ESTABLISHMENT IN YEASTR01GM062300 · NIGMS · DUKE UNIVERSITY · PI LEW, DANIEL J · 2001 to 2016
$5.0M
Computational Biology and Bioinformatics Training ProgramT32GM071340 · NIGMS · DUKE UNIVERSITY · PI MAGWENE, PAUL MITAARI · 2005 to 2020
$3.3M
NIGMS NIH HHS R01 GM062300NIGMS NIH HHS R35 GM122488NIGMS NIH HHS T32 GM071340
6 · The paper itself

Abstract

In many cells, morphogenetic events are coordinated with the cell cycle by cyclin-dependent kinases (CDKs). For example, many mammalian cells display extended morphologies during interphase but round up into more spherical shapes during mitosis (high CDK activity) and constrict a furrow during cytokinesis (low CDK activity). In the budding yeast

Indexed as

Gene Expression Regulation, FungalActin Cytoskeletoncdc42 GTP-Binding Protein, Saccharomyces cerevisiaeCell PolarityCytokinesisFeedback, PhysiologicalG1 Phase Cell Cycle CheckpointsMAP Kinase Kinase KinasesMitosisSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionTime Factorscdc42 GTP-Binding Protein, Saccharomyces cerevisiaeMAP Kinase Kinase KinasesSaccharomyces cerevisiae ProteinsSTE20 protein, S cerevisiae

Identifiers

PMID30459262
PMCPMC6314536
OpenAlexW2900855542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.