Evidence map›Paper›PMID 30459198›Full record

ArticlemBio2018

Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.

Kathrine McAulay, Kohta Saito, Thulasi Warrier, Kathleen Frances Walsh, Laurent Daniel Mathurin, Gertrude Royal-Mardi, Myung Hee Lee, Oksana Ocheretina, Jean William Pape, Daniel W Fitzgerald and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. MakingCell insight · 2026
    Review
  3. Beyond culturability: VBNC-like and differentially culturableFrontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. High variance in quantification ofAntimicrobial agents and chemotherapy · 2024
    Article
  9. Clinical Strains ofPathogens (Basel, Switzerland) · 2024
    Article
  10. Eradication of Drug-TolerantMicroorganisms · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Culture-Free Enumeration ofMicroorganisms · 2022
    Article
  16. Review
  17. Dimethyl fumarate eliminates differentially culturableFrontiers in cellular and infection microbiology · 2022
    Article
  18. Article
  19. Clinically encountered growth phenotypes of tuberculosis-causing bacilli and theirFrontiers in cellular and infection microbiology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Kathrine McAulayCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Kohta SaitoDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York, USA.
Thulasi WarrierDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York, USA.
Kathleen Frances WalshCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Laurent Daniel MathurinLes Centres GHESKIO, Port-au-Prince, Haiti.
Gertrude Royal-MardiLes Centres GHESKIO, Port-au-Prince, Haiti.
Myung Hee LeeCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Oksana OcheretinaCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Jean William PapeCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Daniel W FitzgeraldCenter for Global Health, Weill Cornell Medicine, New York, New York, USA.
Carl F NathanDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York, USA cnathan@med.cornell.edu.ORCID 0000-0002-7744-8896
Cornell University · USGheskio Centers · HT

Funding

Viable but Nonculturable MtbU19AI111143 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI GLICKMAN, MICHAEL S, NATHAN, CARL FRANCIS · 2014 to 2020
$48.6M
T32: Pathogenesis of Infectious Diseases Training ProgramT32AI007613 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROY M. GULICK · 1999 to 2026
$8.8M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Training in pharmacokinetic and pharmacodynamics research in HIV and tuberculosisD43TW010062 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2015 to 2019
$1.8M
Global Health Research Training in HIV and TuberculosisK24AI098627 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI FITZGERALD, DANIEL W · 2012 to 2022
$1.8M
FIC NIH HHS D43 TW010062FIC NIH HHS R25 TW009337NIAID NIH HHS K24 AI098627NIAID NIH HHS T32 AI007613NIAID NIH HHS U19 AI111143
6 · The paper itself

Abstract

Recent reports indicate that the sputum of 80% or more of treatment-naive subjects with tuberculosis recruited in England or South Africa contained more viable

Indexed as

Microbiological TechniquesAdultAntitubercular AgentsColony Count, MicrobialDrug Therapy, CombinationFemaleHaitiHumansIsoniazidMaleMycobacterium tuberculosisPyrazinamideRandomized Controlled Trials as TopicRifampinSputumTuberculosis, PulmonaryAntitubercular AgentsIsoniazidPyrazinamideRifampindifferentially detectable bacteriaearly bactericidal activityMycobacterium tuberculosisrifampinviable but nonculturable bacteria

Identifiers

PMID30459198
PMCPMC6247085
OpenAlexW2901541206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.