ArticleCancer research2019
Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models.
Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic Imaging as Future Technology and Innovation in Brain-Tumour Surgery: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- First worldwide multicenter validation of the POLARIS preclinical polarizer across biological models and imaging paradigms.Research square · 2026Article
- Physiological Interpretation of the Lactate to Pyruvate AUC Ratio for Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- CircIQGAP1-CARM1 axis promotes renal cell carcinoma progression through glycolytic reprogramming.Cell death & disease · 2026Article
- Mitochondrial ribosomal protein L12 mediates metabolic reorganization in clear cell renal cell carcinoma by regulating mitochondrial biosynthesis.Cell communication and signaling : CCS · 2025Article
- O-GlcNAcylation of UBAP2L regulates stress granule formation and sunitinib resistance in clear cell renal cell carcinoma.Journal of experimental & clinical cancer research : CR · 2025Article
- HyperpolarizedInternational journal of molecular sciences · 2023Article
- Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples.Bioengineering (Basel, Switzerland) · 2022Article
- Review
- HyperpolarizedCancers · 2022Article
- Hyperpolarized Micro-NMR Platform for Sensitive Analysis of In Vitro Metabolic Flux in Living Cells.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Integrative pan-cancer analysis and clinical characterization of the N7-methylguanosine (m7G) RNA modification regulators in human cancers.Frontiers in genetics · 2022Article
- The metabolic adaptation evoked by arginine enhances the effect of radiation in brain metastases.Science advances · 2021Article
- Construction of circRNA-based ceRNA network and its prognosis-associated subnet of clear cell renal cell carcinoma.Cancer medicine · 2021Article
- In Vivo Assessment of Metabolic Abnormality in Alport Syndrome Using Hyperpolarized [1-Metabolites · 2021Article
- The use of hyperpolarisedBritish journal of cancer · 2021Review
- HyperpolarizedNMR in biomedicine · 2021Review
- Dynamic volumetric hyperpolarizedMagnetic resonance in medicine · 2021Article
- Hyperpolarized Carbon (Methods in molecular biology (Clifton, N.J.) · 2021Article
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13 authors.
Funding
Abstract
The ever-changing tumor microenvironment constantly challenges individual cancer cells to balance supply and demand, presenting tumor vulnerabilities and therapeutic opportunities. Everolimus and temsirolimus are inhibitors of mTOR (mTORi) approved for treating metastatic renal cell carcinoma (mRCC). However, treatment outcome varies greatly among patients. Accordingly, administration of mTORi in mRCC is diminishing, which could potentially result in missing timely delivery of effective treatment for select patients. Here, we implemented a clinically applicable, integrated platform encompassing a single dose of [1-
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