ArticleJournal of Ayurveda and integrative medicine
Assessment of bioavailability of gold bhasma in human participants - A pilot study.
Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 20 citations in OpenAlex.
- Article
- Antiviral Activity of Svarnvir-IV Tablet Assayed for Activity Against SARS-CoV-2 In Vitro.Cureus · 2023Article
- Swarna Bindu Prashana-an Ancient Approach to Improve the Infant's Immunity.Biological trace element research · 2021Review
- Ayurveda and Allopathic Therapeutic Strategies in Coronavirus Pandemic Treatment 2020.Current pharmacology reports · 2020Review
- COVID-19 pandemic: A pragmatic plan for ayurveda intervention.Journal of Ayurveda and integrative medicineArticle
- Nanostructured gold in ancient Ayurvedic calcined drug 'swarnabhasma'.Journal of Ayurveda and integrative medicineArticle
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioavailability of the well-known Ayurvedic drug Swarnabhasma (gold bhasma or calcined gold) is unknown. It is orally administered either sublingually or directly with various Anupanas like black pepper powder (Piper nigrum Linn.) and cow ghee in the dose range of 15-240 mg by Ayurvedic physicians. Study of bioavailability of Swarnabhasma is necessary as this metal-derived drug is administered for long duration for rejuvenation. The pilot study was carried out in healthy human male participants to assess bioavailability of Swarnabhasma in three doses, viz. 30 mg plain sublingual, 30 mg oral dose mixed with black pepper powder (250 mg) and cow ghee (2.5 gm); and 240 mg oral dose mixed with black pepper powder (250 mg) and cow ghee (2.5 gm). Blood samples were withdrawn at 0, 1, 2 and 4 h after administration of dose. Estimation of gold levels in blood was carried out by inductively coupled plasma mass spectrometry (ICP-MS). Results show that gold is absorbed in traces from single dose of Swarnabhasma. Maximum concentration of gold was bioavailable from 30 mg sublingual dose with C
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