Evidence map›Paper›PMID 30458950›Full record

ArticleAmerican journal of preventive medicine2018

NIH Primary and Secondary Prevention Research in Humans During 2012-2017.

David M Murray, Jennifer Villani, Ashley J Vargas, Jocelyn A Lee, Ranell L Myles, Jessica Y Wu, Patricia L Mabry, Sheri D Schully

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Health Literacy Research Funded by the NIH for Disease Prevention.Health literacy research and practice · 2020
    Article
  5. Review
  6. Article
  7. Scaling up Evidence-Based Interventions in US Public Systems to Prevent Behavioral Health Problems: Challenges and Opportunities.Prevention science : the official journal of the Society for Prevention Research · 2019
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David M MurrayOffice of Disease Prevention, NIH, Rockville, Maryland. Electronic address: david.murray2@nih.gov.
Jennifer VillaniOffice of Disease Prevention, NIH, Rockville, Maryland.
Ashley J VargasOffice of Disease Prevention, NIH, Rockville, Maryland.
Jocelyn A LeeOffice of Disease Prevention, NIH, Rockville, Maryland.
Ranell L MylesOffice of Disease Prevention, NIH, Rockville, Maryland.
Jessica Y WuUniversity of California Research Initiatives, University of California, Office of the President, Oakland, California.
Patricia L MabryIndiana University Network Science Institute and School of Public Health-Bloomington, Indiana University, Bloomington, Indiana.
Sheri D SchullyOffice of Disease Prevention, NIH, Rockville, Maryland.
Office of Disease Prevention and Health Promotion · USIndiana University Bloomington · USUniversity of California System · US

Funding

Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

introductionThis paper provides the first detailed analysis of the NIH prevention research portfolio for primary and secondary prevention research in humans and related methods research.

methodsThe Office of Disease Prevention developed a taxonomy of 128 topics and applied it to 11,082 projects representing 91.7% of all new projects and 84.1% of all dollars used for new projects awarded using grant and cooperative agreement activity codes that supported research in fiscal years 2012-2017. Projects were coded in 2016-2018 and analyzed in 2018.

resultsOnly 16.7% of projects and 22.6% of dollars were used for primary and secondary prevention research in humans or related methods research. Most of the leading risk factors for death and disability in the U.S. were selected as an outcome in <5% of the projects. Many more projects included an observational study, or an analysis of existing data, than a randomized intervention. These patterns were consistent over time.

conclusionsThe appropriate level of support for primary and secondary prevention research in humans from NIH will differ by field and stage of research. The estimates reported here may be overestimates, as credit was given for a project even if only a portion of that project addressed prevention research. Given that 74% of the variability in county-level life expectancy across the U.S. is explained by established risk factors, it seems appropriate to devote additional resources to developing and testing interventions to address those risk factors.

Indexed as

Financing, GovernmentNational Institutes of Health (U.S.)Primary PreventionSecondary PreventionHealth Services ResearchHumansUnited States

Identifiers

PMID30458950
PMCPMC6251492
OpenAlexW2898275345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.