Evidence map›Paper›PMID 30458805›Full record

Trial reportRespiratory research2018

Combination of inspiratory and expiratory muscle training in same respiratory cycle versus different cycles in COPD patients: a randomized trial.

Wenhui Xu, Rui Li, Lili Guan, Kai Wang, Yuhe Hu, Limei Xu, Luqian Zhou, Rongchang Chen, Xin Chen

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02326181 naunknown statusnot on this map

Effects of Inspiratory and Respiratory Pressure Threshold Training in Patients With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorZhujiang HospitalRan2015 to 2016Enrolled80ConditionsChronic Obstructive Pulmonary Disease(COPD)Armsinspiratory pressure training group, mixed training group
NCT05587829 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effects of Diaphragm and Abdominal Muscle Training on Pulmonary Function Testing and Dyspnea Among Chronic Obstructive Pulmonary Disease Patients.

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2023Enrolled50ConditionsChronic Obstructive Pulmonary DiseaseArms• Diaphragmatic breathing technique, basic breathing technique
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wenhui XuDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Rui LiDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Lili GuanDepartment of Respiratory Medicine, The State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Guangzhou, 510120, China.
Kai WangDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Yuhe HuDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Limei XuDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China.
Luqian ZhouDepartment of Respiratory Medicine, The State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Guangzhou, 510120, China.
Rongchang ChenDepartment of Respiratory Medicine, The State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, 151 Yanjiang Road, Guangzhou, 510120, China. chenrc@vip.163.com.
Xin ChenDepartment of Respiratory Medicine, Zhujiang Hosptial, Southern Medical University, 253 Gongye Road, Guangzhou, 510282, China. chen_xin1020@163.com.ORCID http://orcid.org/0000-0002-1920-8835
Southern Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNZhujiang Hospital · CN

Funding

Clinical Research training program of Southern Medical University LC2016PY032Guangzhou Innovation and Entrepreneurship Education Project of Universities 201709T26National Key R&D Program of China 2017YFC1310601Special Funds for the Cultivation of Guangdong College Students' Scientific and Technological Innovation PDJHB0101The Guangzhou Healthcare Collaborative Innovation Major Project 201604020012
6 · The paper itself

Abstract

backgroundDifference between combined inspiratory and expiratory muscle training in same respiratory cycle or different cycles remained unclarified. We explored the difference between both patterns of combined trainings in patients with COPD.

methodsIn this randomized, open-label, controlled trial, stable COPD subjects trained for 48 minutes daily, for 8 weeks, using a monitoring device for quality control. Ninety-two subjects were randomly and equally assigned for sham training, inspiratory muscle training(IMT), combined inspiratory and expiratory muscle training in same cycle(CTSC) or combined inspiratory and expiratory muscle training in different cycles(CTDC). Respiratory muscle strength, as the primary endpoint, was measured before and after training. Registry: ClinicalTrials.gov (identifier: NCT02326181).

resultsRespiratory muscle training improved maximal inspiratory pressure(PImax), while no significant difference was found in PImax among IMT, CTSC and CTDC. Maximal expiratory pressure(PEmax) in CTSC and CTDC was greater than IMT(P = 0.026, and P=0.04, respectively) and sham training (P = 0.001). IMT, CTSC, and CTDC shortened inhalation and prolonged exhalation(P < 0.01). Subjects with respiratory muscle weakness in IMT and CTDC exhibited greater increase in PImax than those without. IMT, CTSC and CTDC showed no difference in symptoms and quality of life scales among themselves(P > 0.05).

conclusionBoth patterns of CTSC and CTDC improved inspiratory and expiratory muscle strength, while IMT alone only raised PImax. Respiratory muscle training might change the respiratory cycles, and be more beneficial for COPD patients with inspiratory muscle weakness.

Indexed as

AgedBreathing ExercisesExhalationFemaleHumansInhalationMaleMiddle AgedMuscle StrengthPulmonary Disease, Chronic ObstructiveRespiratory MusclesChronic obstructive pulmonary diseaseCombined respiratory muscle trainingExpiratory muscle trainingInspiratory muscle training

Identifiers

PMID30458805
PMCPMC6245535
OpenAlexW2900683802

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.