Evidence map›Paper›PMID 30458758›Full record

SynthesisBMC health services research2018

The weekend effect: does hospital mortality differ by day of the week? A systematic review and meta-analysis.

Kate Honeyford, Elizabeth Cecil, Michelle Lo, Alex Bottle, Paul Aylin

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC health services research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The weekend effect in sepsis and septic shock: a 5-year US national study.Proceedings (Baylor University. Medical Center) · 2026
    Article
  11. Article
  12. Development of a Health Text Message System to Support Stroke Prevention: A Component of the Love Your Brain Digital Platform.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Comparing mortality in the elderly after proximal femur fractures and coxarthrosis: the effect of individual health characteristics and day of surgery.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kate HoneyfordDepartment of Primary Care and Public Health, Dr Foster Unit at Imperial College, 3 Dorset Rise, London, EC4Y 8EN, UK. k.honeyford@imperial.ac.uk.ORCID http://orcid.org/0000-0002-5533-7693
Elizabeth CecilDepartment of Primary Care and Public Health, Dr Foster Unit at Imperial College, 3 Dorset Rise, London, EC4Y 8EN, UK.
Michelle LoDepartment of Family Medicine and Primary Healthcare, Hospital Authority, Hong Kong, Hong Kong.
Alex BottleDepartment of Primary Care and Public Health, Dr Foster Unit at Imperial College, 3 Dorset Rise, London, EC4Y 8EN, UK.
Paul AylinDepartment of Primary Care and Public Health, Dr Foster Unit at Imperial College, 3 Dorset Rise, London, EC4Y 8EN, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe concept of a weekend effect, poorer outcomes for patients admitted to hospitals at the weekend is not new, but is the focus of debate in England. Many studies have been published which consider outcomes for patients on admitted at the weekend. This systematic review and meta-analysis aims to estimate the effect of weekend admission on mortality in UK hospitals.

methodsThis is a systematic review and meta-analysis of published studies on the weekend effect in UK hospitals. We used EMBASE, MEDLINE, HMIC, Cochrane, Web of Science and Scopus to search for relevant papers. We included systematic reviews, randomised controlled trials and observational studies) on patients admitted to hospital in the UK and published after 2001. Our outcome was death; studies reporting mortality were included. Reviewers identified studies, extracted data and assessed the quality of the evidence, independently and in duplicate. Discrepancy in assessment was considered by a third reviewer. All meta-analyses were performed using a random-effects meta-regression to incorporate the heterogeneity into the weighting.

resultsForty five articles were included in the qualitative synthesis. 53% of the articles concluded that outcomes for patients either undergoing surgery or admitted at the weekend were worse. We included 39 in the meta-analysis which contributed 50 separate analyses. We found an overall effect of 1.07 [odds ratio (OR)] (95%CI:1.03-1.12), suggesting that patients admitted at the weekend had higher odds of mortality than those admitted during the week. Sub-group analyses suggest that the weekend effect remained when measures of case mix severity were included in the models (OR:1.06 95%CI:1.02-1.10), but that the weekend effect was not significant when clinical registry data was used (OR:1.03 95%CI: 0.98-1.09). Heterogeneity was high, which may affect generalisability.

conclusionsDespite high levels of heterogeneity, we found evidence of a weekend effect in the UK, even after accounting for severity of disease. Further work is required to examine other potential explanations for the "weekend effect" such as staffing levels and other organisational factors.

trial registrationPROSPERO International Prospective Register of Systematic Reviews -registration number: CRD42016041225 .

Indexed as

EnglandGastrointestinal HemorrhageHospitalizationHospital MortalityHumansPrognosisProspective StudiesPulmonary Disease, Chronic ObstructiveStrokeTime FactorsHospitalMortalityQuality of careWeekend effect

Identifiers

PMID30458758
PMCPMC6245775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.