ArticleBMC plant biology2018
Two MYB transcription factors (CsMYB2 and CsMYB26) are involved in flavonoid biosynthesis in tea plant [Camellia sinensis (L.) O. Kuntze].
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.
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37 citing papers in PubMed.
- Review
- Multi-dimensional regulation of tea leaf development: morphogenesis, hormone-transcriptional networks, environmental factors, and artificial cultivation practices.Frontiers in plant science · 2026Review
- Multi-omics analyses reveal the effects of layerage and grafting on flavonoid synthesis and accumulation inHorticulture research · 2025Article
- Genome wide association analysis of flavour related metabolites in tea germplasm [Camellia sinensis (L.) Kuntze] from Assam using a genotyping by sequencing strategy.BMC plant biology · 2025Article
- Transcriptome of Two-Hybrid Poplar (Biology · 2025Article
- Function of Anthocyanin and Chlorophyll Metabolic Pathways in the Floral Sepals Color Formation in Different Hydrangea Cultivars.Plants (Basel, Switzerland) · 2025Article
- Integrated transcriptomic and metabolomic analysis of flavonoid biosynthesis in cigar tobacco leaves under variable nitrogen regimes.Frontiers in plant science · 2025Article
- An integrated transcriptomic and metabolomic analysis of black spot disease in Jinggang honey pomelo reveals underlying resistance mechanisms.Frontiers in microbiology · 2025Article
- Heterologous Expression of MYB Gene (International journal of molecular sciences · 2024Article
- Association analysis of BSA-seq, BSR-seq, and RNA-seq reveals key genes involved in purple leaf formation in a tea population (Horticulture research · 2024Article
- Differential Response of MYB Transcription Factor Gene Transcripts to Circadian Rhythm in Tea Plants (International journal of molecular sciences · 2024Article
- Metabolomic and transcriptomic analysis of the flavonoid biosynthesis pathway inFrontiers in plant science · 2024Article
- Article
- Characterization of the Difference between Day and Night Temperatures on the Growth, Photosynthesis, and Metabolite Accumulation of Tea Seedlings.International journal of molecular sciences · 2023Article
- Phylogenetic Analysis ofBiomolecules · 2023Article
- Designing plant flavonoids: harnessing transcriptional regulation and enzyme variation to enhance yield and diversity.Frontiers in plant science · 2023Review
- CcMYB12 Positively Regulates Flavonoid Accumulation during Fruit Development inInternational journal of molecular sciences · 2022Article
- De novo transcriptome sequencing of Impatiens uliginosa and the analysis of candidate genes related to spur development.BMC plant biology · 2022Article
- CsMYB Transcription Factors Participate in Jasmonic Acid Signal Transduction in Response to Cold Stress in Tea Plant (Plants (Basel, Switzerland) · 2022Article
- Transcriptome-wide NaBIOTECH · 2022Article
Corrections and comments
- Erratum issued
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6 authors.
Funding
Abstract
backgroundFlavonoids are secondary metabolites that play important roles in the entire tea plant life cycle and have potential health-promoting properties. MYB transcription factors (TFs) are considered potentially important regulators of flavonoid biosynthesis in plants. However, the molecular mechanisms by which MYB TFs regulate the flavonoid pathway in tea plant remain unknown.
resultsIn this study, two R2R3-MYB TFs (CsMYB2 and CsMYB26) involved in flavonoid biosynthesis in tea plant were investigated. The genes encoding CsMYB2 and CsMYB26 were cloned from the tea plant cultivar 'Longjing 43'. Phylogenetic analysis showed that CsMYB2 and CsMYB26 were grouped into the proanthocyanidin biosynthesis-related MYB clade. Multiple sequence alignment revealed that conserved motif 1 in the two MYB factors was related to the bHLH TF. Subcellular localization assays suggested that CsMYB2 localized in the nucleus. Promoter analysis indicated that CsMYB2, CsMYB26 and the related structural genes contain MYB recognition elements. The expression levels of the CsMYB2 and CsMYB26 genes and the structural genes in the flavonoid biosynthesis pathway were determined in leaves from various sites in the two tea plant cultivars 'Longjing 43' and 'Baiye 1 hao'.
conclusionsThe expression levels of these genes were correlated with the accumulated flavonoid content. The results demonstrated that the expression level of CsF3'H may be regulated by CsMYB2 and that CsMYB26 expression is positively correlated with CsLAR expression. The relative transcriptional level of CsMYB26 may be the main reason for the different epigallocatechin contents between the tea plant cultivars 'Longjing 43' and 'Baiye 1 hao'. Our results will serve as a reference for the potential regulatory roles of CsMYB2 and CsMYB26 in flavonoid biosynthesis in tea plant and may also assist biologists in improving tea quality.
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