ArticleAmerican journal of speech-language pathology2018
Clinical Progression in Four Cases of Primary Progressive Apraxia of Speech.
Article in American journal of speech-language pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- Deep learning-derived measures of sound-level accuracy in primary progressive apraxia of speech: A feasibility pipeline with descriptive evidence from two cases.Clinical linguistics & phonetics · 2026Article
- Diagnosing Apraxia of Speech in Children and Adults When There Is No Gold Standard: A Scoping Review About the Diagnostic Process.American journal of speech-language pathology · 2026Article
- Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech.Journal of neurology · 2024Article
- Efficacy of LSVT LOUDBrain sciences · 2024Article
- Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum.Brain : a journal of neurology · 2024Article
- Normative Values for Word Syllable Duration With Interpretation in a Large Sample of Stroke Survivors With Aphasia.American journal of speech-language pathology · 2023Article
- Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features.Brain and language · 2023Article
- Rate Modulation Abilities in Acquired Motor Speech Disorders.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Three-Dimensional Speech Profiles in Stroke Aphasia and Apraxia of Speech.American journal of speech-language pathology · 2023Article
- An Update on Apraxia of Speech.Current neurology and neuroscience reports · 2023Review
- Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech.European journal of neurology · 2023Article
- Acoustic Analysis and Neuroimaging Correlates of Diadochokinetic Rates in Mild-Moderate Primary Progressive Apraxia of Speech.Brain and language · 2023Article
- The Apraxia of Speech Rating Scale: Reliability, Validity, and Utility.American journal of speech-language pathology · 2023Article
- Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia.Journal of Alzheimer's disease reports · 2023Article
- Neuropsychological Profiles of Patients with Progressive Apraxia of Speech and Aphasia.Journal of the International Neuropsychological Society : JINS · 2022Article
- A Preliminary Report of Network Electroencephalographic Measures in Primary Progressive Apraxia of Speech and Aphasia.Brain sciences · 2022Article
- Progressive apraxia of speech: delays to diagnosis and rates of alternative diagnoses.Journal of neurology · 2021Article
- Assessing Change in Communication Limitations in Primary Progressive Apraxia of Speech and Aphasia: A 1-Year Follow-Up Study.American journal of speech-language pathology · 2021Article
- Motor Speech Disorders and Communication Limitations in Progressive Supranuclear Palsy.American journal of speech-language pathology · 2021Article
- Survival Analysis in Primary Progressive Apraxia of Speech and Agrammatic Aphasia.Neurology. Clinical practice · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Purpose: This case series details the clinical progression of patients with primary progressive apraxia of speech (PPAOS) to illustrate, using several methods and supplemental material examples, the changes that occur in speech and language functioning in this patient population. Method: Four patients who presented with PPAOS were followed between 5 and 6 years. Two patients had predominant articulatory abnormalities (termed phonetic PPAOS), 1 had predominant prosodic abnormalities (prosodic PPAOS), and 1 had relatively equal articulatory and prosodic abnormalities (mixed PPAOS). Detailed speech (including acoustics), language, neurologic, and neuropsychological data were collected. Results: At initial exam, the patients ranged from 60 to 77 years old, with presenting disease duration of 1.5-10 years. Although all patients presented with an isolated apraxia of speech, all developed varying degrees of aphasia and dysarthria. Patients with phonetic PPAOS developed relatively more severe aphasia than the other 2 patients. All patients eventually had severe functional communication limitations and required alternative or augmentative means of communication, although at varying times postonset of their initial speech problem. Two patients developed dysphagia, 3 showed mild-moderate Parkinsonism, and 2 developed depression. For all patients, simple temporal acoustic measurements documented slowed speech rate over time. Conclusions: This case series demonstrates that patients who initially present with PPAOS may develop aphasia and dysarthria, cognitive and behavioral changes, and other neurologic signs. Whether these changes can be predicted by the perceptual characteristics of the apraxia of speech is yet to be determined. The detailed longitudinal profiles provide valuable clinical insight into the progression of disease in people with PPAOS. Supplemental Material: https://doi.org/10.23641/asha.7051616.
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