Evidence map›Paper›PMID 30458132›Full record

ArticleDevelopmental cell2018

The Inner Nuclear Membrane Takes On Lipid Metabolism.

Holly Merta, Shirin Bahmanyar

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Holly MertaDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.
Shirin BahmanyarDepartment of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA. Electronic address: shirin.bahmanyar@yale.edu.
Yale University · US

Funding

Defining the role of lipid metabolism in nuclear envelope identity and dynamicsR01GM131004 · NIGMS · YALE UNIVERSITY · PI Shirin Bahmanyar · 2019 to 2026
$2.8M
NIGMS NIH HHS R01 GM131004
6 · The paper itself

Abstract

Challenging the idea of the inner nuclear membrane (INM) being an inert compartment, recent work in S. cerevisiae shows that the INM can metabolize lipids and that local lipid metabolism can regulate transcription in response to lipid availability, suggesting a functional role for the INM in cellular lipid homeostasis.

Indexed as

Nuclear EnvelopeSaccharomyces cerevisiaeLipid DropletsLipid MetabolismLipidsMembrane ProteinsLipidsMembrane Proteins

Identifiers

PMID30458132
OpenAlexW2901972008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.