Evidence map›Paper›PMID 30457997›Full record

ArticlePloS one2018

Feature selection for the accurate prediction of septic and cardiogenic shock ICU mortality in the acute phase.

Alexander Aushev, Vicent Ribas Ripoll, Alfredo Vellido, Federico Aletti, Bernardo Bollen Pinto, Antoine Herpain, Emiel Hendrik Post, Eduardo Romay Medina, Ricard Ferrer, Giuseppe Baselli and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Alexander AushevIntelligent Data Engineering and Artificial Intelligence (IDEAI) Research Center, Computer Science, Universitat Politècnica de Catalunya, Barcelona, Spain.ORCID 0000-0002-8103-2834
Vicent Ribas RipollEurecat, Centre Tecnològic de Catalunya, eHealth, Data Analytics in Omics, Barcelona, Spain.
Alfredo VellidoIntelligent Data Engineering and Artificial Intelligence (IDEAI) Research Center, Computer Science, Universitat Politècnica de Catalunya, Barcelona, Spain.
Federico AlettiDepartment of Bioengineering, University of California San Diego, La Jolla, CA, United States of America.
Bernardo Bollen PintoHemodynamic Research Group, Université de Genève, Geneva, Switzerland.
Antoine HerpainDepartment of Intensive Care, Hôpital Erasme - Université Libre de Bruxelles, Brussels, Belgium.
Emiel Hendrik PostDepartment of Intensive Care, Hôpital Erasme - Université Libre de Bruxelles, Brussels, Belgium.
Eduardo Romay MedinaHospital Universitari Mutua de Terrassa, Terrassa, Spain.
Ricard FerrerCritical Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Giuseppe BaselliDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano - Piazza Leonardo da Vinci, Milan, Italy.
Karim BendjelidHemodynamic Research Group, Université de Genève, Geneva, Switzerland.
Universitat Politècnica de Catalunya · ESUniversité Libre de Bruxelles · BEUniversity of Geneva · CHCentre Tecnologic de Telecomunicacions de Catalunya · ESMútua Terrassa · ESPolitecnico di Milano · ITUniversitat Autònoma de Barcelona · ESUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulatory shock is a life-threatening disease that accounts for around one-third of all admissions to intensive care units (ICU). It requires immediate treatment, which is why the development of tools for planning therapeutic interventions is required to deal with shock in the critical care environment. In this study, the ShockOmics European project original database is used to extract attributes capable of predicting mortality due to shock in the ICU. Missing data imputation techniques and machine learning models were used, followed by feature selection from different data subsets. Selected features were later used to build Bayesian Networks, revealing causal relationships between features and ICU outcome. The main result is a subset of predictive features that includes well-known indicators such as the SOFA and APACHE II scores, but also less commonly considered ones related to cardiovascular function assessed through echocardiograpy or shock treatment with pressors. Importantly, certain selected features are shown to be most predictive at certain time-steps. This means that, as shock progresses, different attributes could be prioritized. Clinical traits obtained at 24h. from ICU admission are shown to accurately predict cardiogenic and septic shock mortality, suggesting that relevant life-saving decisions could be made shortly after ICU admission.

Indexed as

Intensive Care UnitsAPACHEFemaleHospital MortalityHumansMaleModels, TheoreticalPredictive Value of TestsShock, CardiogenicShock, Septic

Identifiers

PMID30457997
PMCPMC6245679
OpenAlexW2951942155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.