Evidence map›Paper›PMID 30457654›Full record

ArticleOphthalmic surgery, lasers & imaging retina2018

Visualizing Structure and Vascular Interactions: Macular Nonperfusion in Three Capillary Plexuses.

Justin J Park, Christopher S Chung, Amani A Fawzi

Open access · greenAbstract read
In one paragraph

Article in Ophthalmic surgery, lasers & imaging retina, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin J Park
Christopher S Chung
Amani A Fawzi

Funding

Functional Retinal Imaging to Monitor Pharmaco-Therapies in Diabetic RetinopathyDP3DK108248 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FAWZI, AMANI A, ZHANG, HAO F · 2015 to 2015
$1.9M
NIDDK NIH HHS DP3 DK108248
6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo assess the relationship between retinal vascular and structural changes in the superficial, middle, and deep capillary plexuses (SCP, MCP, DCP) using optical coherence tomography angiography (OCTA) and en face OCT. PATIENTS AND

methodsPatients with diabetic retinopathy were imaged using the Cirrus HD-OCT with AngioPlex. Using manual segmentation of the retinal layers, the authors compared OCTA to en face OCT images to examine corresponding patterns in each of the three capillary plexuses.

resultsAreas of decreased perfusion and capillary dropout on OCTA were found to be associated with three corresponding lesions on en face OCT: hyporeflectivity, cystic edema, and hard exudates. Vascular changes in individual capillary plexuses corresponded with structural changes in their respective perfused retinal layers.

conclusionsUsing manual segmentation on OCTA, the authors provide a framework to visualize the relationship between vascular pathology on OCTA and structural changes on en face OCT within specific capillary plexuses. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e182-e190.].

Indexed as

Visual AcuityAdultAgedCapillariesDiabetic RetinopathyFemaleFluorescein AngiographyFundus OculiHumansMacula LuteaMaleMiddle AgedProspective StudiesRetinal VesselsTomography, Optical Coherence

Identifiers

PMID30457654
PMCPMC6408874
OpenAlexW2901477699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.