Evidence map›Paper›PMID 30457092›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Acute Flavivirus and Alphavirus Infections among Children in Two Different Areas of Kenya, 2015.

Jimmy Hortion, Francis M Mutuku, Ana L Eyherabide, David M Vu, Derek B Boothroyd, Elysse N Grossi-Soyster, Charles H King, Bryson A Ndenga, A Desiree LaBeaud

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Temporal Variation and Human Host Predominance inPathogens (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Jimmy HortionDivision of Infectious Diseases, Department of Pediatrics, Stanford University School of Medicine, Stanford, California.
Francis M MutukuDepartment of Environment and Health Sciences, Technical University of Mombasa, Mombasa, Kenya.
Ana L EyherabideDepartamento de Pediatría, Sanatorio de Niños, Rosario, Argentina.
David M VuDivision of Infectious Diseases, Department of Pediatrics, Stanford University School of Medicine, Stanford, California.
Derek B BoothroydQuantitative Science Unit, Department of Medicine, Stanford University School of Medicine, Stanford, California.
Elysse N Grossi-SoysterDepartamento de Pediatría, Sanatorio de Niños, Rosario, Argentina.
Charles H KingCenter for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio.
Bryson A NdengaCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
A Desiree LaBeaudDepartamento de Pediatría, Sanatorio de Niños, Rosario, Argentina.
Stanford University · USCase Western Reserve University · USÉcole Normale Supérieure de Lyon · FRKenya Medical Research Institute · KETechnical University of Mombasa · KE

Funding

The child health impacts of overlapping vector-borne diseases in KenyaR01AI102918 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud · 2013 to 2026
$7.7M
NIAID NIH HHS R01 AI102918
6 · The paper itself

Abstract

Alphaviruses and flaviviruses are known to be endemic in Eastern Africa, but few data are available to evaluate the prevalence of these infections. This leads to missed opportunities for prevention against future outbreaks. This cohort study investigated the frequency of alphavirus and flavivirus incident infections in two regions of Kenya and identified potential risk factors. Seroconversions for alphavirus and flavivirus infections were identified by immunoglobulin G enzyme-linked immunosorbent assay (IgG-ELISA) in a cohort of 1,604 acutely ill children over the year 2015. The annual incidence was 0.5% (0.2-1.2%) for alphaviruses and 1.2% (0.7-2.2%) for flaviviruses. Overall, seroprevalence was significantly higher for alphaviruses in western Kenya than on the coast (

Indexed as

Acute DiseaseAdolescentAlphavirusAlphavirus InfectionsAntibodies, ViralChildChild, PreschoolCohort StudiesEnzyme-Linked Immunosorbent AssayFemaleFlavivirusFlavivirus InfectionsHumansInfantInfant, NewbornKenyaAntibodies, Viral

Identifiers

PMID30457092
PMCPMC6335892
OpenAlexW2901260129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.