Evidence map›Paper›PMID 30457089›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Evidence of Self-Medication with Chloroquine before Consultation for Malaria in the Southern Pacific Coast Region of Colombia.

Gustavo Diaz, Alvaro Mauricio Lasso, Claribel Murillo, Lidia M Montenegro, Diego F Echeverry

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gustavo DiazUniversidad Icesi, Cali, Colombia.
Alvaro Mauricio LassoCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Claribel MurilloCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Lidia M MontenegroCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Diego F EcheverryCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia.
Centro Internacional de Entrenamiento e Investigaciones Medicas · COIcesi University · CO

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Vector/Host-Parasite Interface of Leishmaniasis in ColombiaD43TW006589 · FIC · YALE UNIVERSITY · PI GORE SARAVIA, NANCY, TSCHUDI, CHRISTIAN · 2003 to 2024
$4.3M
FIC NIH HHS D43 TW006589FIC NIH HHS D43 TW010540
6 · The paper itself

Abstract

Self-medication with antimalarial drugs is a major factor in the development of drug resistance, exerting subtherapeutic drug pressure on circulating parasite populations. Data on self-medication with antimalarials from the Southern Pacific coast region of Colombia, where 4-aminoquinolines resistance and political instability prevail, are vital to elimination strategies. We present results of an exploratory study of 254 individuals having malaria symptoms who sought malaria diagnosis in two hospitals in Tumaco, Department of Nariño, Colombia. Thirty-two percent (82/254) of participants had positive Saker-Solomons urine tests, indicating self-medication with chloroquine (CQ) before consultation for diagnosis. Notably, among 30 pregnant women participating in the study, 43% were Saker--Solomons positive. Molecular analysis of the K76T position encoded by the

Indexed as

AdolescentAdultAllelesAntimalarialsChloroquineColombiaDrug Resistance, MultipleFemaleHumansMalaria, FalciparumMaleMembrane Transport ProteinsMiddle AgedMutationPlasmodium falciparumPregnancyAntimalarialsChloroquineMembrane Transport ProteinsPfCRT protein, Plasmodium falciparumProtozoan Proteins

Identifiers

PMID30457089
PMCPMC6335913
OpenAlexW2900589651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.