Evidence map›Paper›PMID 30456898›Full record

Observational studyBrain and behavior2018

Intracranial artery stenosis magnetic resonance imaging aetiology and progression study: Rationale and design.

Yongjun Han, Huiyu Qiao, Shuo Chen, Jing Jing, Yuesong Pan, Dongye Li, Yang Liu, Xia Meng, Yilong Wang, Xihai Zhao and 1 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yongjun HanCenter for Brain Disorders Research, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
Huiyu QiaoDepartment of Biomedical Engineering, Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China.
Shuo ChenDepartment of Biomedical Engineering, Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China.
Jing JingDepartment of Neurology, Beijing Tiantan hospital, Capital Medical University, Beijing, China.
Yuesong PanDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China.ORCID 0000-0003-3082-6789
Dongye LiCenter for Brain Disorders Research, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
Yang LiuDepartment of Radiology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Xia MengDepartment of Neurology, Beijing Tiantan hospital, Capital Medical University, Beijing, China.
Yilong WangDepartment of Neurology, Beijing Tiantan hospital, Capital Medical University, Beijing, China.
Xihai ZhaoDepartment of Biomedical Engineering, Center for Biomedical Imaging Research, Tsinghua University School of Medicine, Beijing, China.ORCID 0000-0001-8953-0566
ICASMAP investigators
Capital Medical University · CNTsinghua University · CNChinese Institute for Brain Research · CNNorthern Jiangsu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been shown that intracranial artery stenosis (ICAS) plays a key role in Chinese ischemic stroke or transient ischemic attack (TIA) patients. Many vascular diseases can lead to ICAS, such as atherosclerosis, dissection, vasculitis, moyamoya disease, and reversible cerebral vasoconstriction syndrome (RCVS). In addition, progression of intracranial atherosclerotic disease (ICAD) will increase the risk of ischemic cerebrovascular events. The ICASMAP study primarily aims to determine the etiology and disease distribution of ICAS using noninvasive magnetic resonance (MR) imaging and evaluate the rate for progression of ICAD in symptomatic population.

methodsThe ICASMAP study is a prospective, observational, and multicenter study by recruiting 300 subjects (18-80 years old) with recent stroke or TIA (within 2 weeks after onset of symptoms) in China. All the subjects will undergo MR imaging examination including brain and intracranial artery MR imaging at baseline. In addition, the clinical risk factors will be collected and blood biomarkers will be tested. A subgroup of more than 200 subjects who were diagnosed with ICAD according to baseline MR imaging will be followed up for 2 years. During the follow-up study, MR imaging examination will be performed at 12 and 24 months. The primary end point is presence of progression of intracranial artery atherosclerotic plaques.

conclusionsThe ICASMAP study investigates the etiology of ICAS and progression of ICAD in Chinese stroke patients and may help to improve the precise diagnosis and intervention of ICAS and stroke prevention.

Indexed as

AdolescentAdultAgedAged, 80 and overCerebrovascular DisordersChinaConstriction, PathologicDisease ProgressionFemaleFollow-Up StudiesHumansIntracranial ArteriosclerosisIschemic Attack, TransientMagnetic Resonance ImagingMaleMiddle Agedatherosclerosisetiologyintracranial arterymagnetic resonance imagingprogressionstenosis

Identifiers

PMID30456898
PMCPMC6305940
OpenAlexW2901611171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.