Evidence map›Paper›PMID 30456870›Full record

ArticleAPMIS : acta pathologica, microbiologica, et immunologica Scandinavica2018

WHO laboratory validation of Xpert

Susanne Jacobsson, Iryna Boiko, Daniel Golparian, Karel Blondeel, James Kiarie, Igor Toskin, Rosanna W Peeling, Magnus Unemo

Abstract readValidation Study
In one paragraph

Article in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. [Point-of-care tests for sexually transmitted infections-what is the current status?]Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Article
  5. Review
  6. Detection and characterisation of Xpert CT/NG assayEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Detection ofAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Maximizing theJournal of clinical microbiology · 2024
    Article
  19. Article
  20. Assessment ofLe infezioni in medicina · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susanne JacobssonWHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Iryna BoikoClinical Laboratory Department, Ternopil Regional Clinical Dermatovenerologic Dispensary, Ternopil, Ukraine.
Daniel GolparianWHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Karel BlondeelDepartment of Reproductive Health and Research, World Health Organization (WHO), Geneva, Switzerland.
James KiarieDepartment of Reproductive Health and Research, World Health Organization (WHO), Geneva, Switzerland.
Igor ToskinDepartment of Reproductive Health and Research, World Health Organization (WHO), Geneva, Switzerland.
Rosanna W PeelingLondon School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Magnus UnemoWHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Funding

Department of Reproductive Health and Research, World Health Organization (WHO)Örebro County Council Research Committee and the Foundation for Medical Research at Örebro University Hospital
6 · The paper itself

Abstract

Effective tests for diagnosis of sexually transmitted infections (STIs), used point of care to inform treatment and management decisions, are urgently needed. We evaluated the analytical sensitivity and specificity of the Xpert

Indexed as

Point-of-Care SystemsCross ReactionsFalse Positive ReactionsFemaleHumansMaleMolecular Diagnostic TechniquesSensitivity and SpecificitySexually Transmitted DiseasesChlamydia trachomatisGeneXpertNeisseria gonorrhoeaepoint of careTrichomonas vaginalisXpert® CT/NGXpert® TV

Identifiers

PMID30456870
PMCPMC6488022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.