Evidence map›Paper›PMID 30456777›Full record

ArticleJournal of biomedical materials research. Part A2019

Tuning of hydrogel stiffness using a two-component peptide system for mammalian cell culture.

Alessandra Scelsi, Brigida Bochicchio, Andrew Smith, Victoria L Workman, Luis A Castillo Diaz, Alberto Saiani, Antonietta Pepe

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  15. Self-Assembling Hydrogel Structures for Neural Tissue Repair.ACS biomaterials science & engineering · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandra ScelsiLaboratory of Bioinspired Materials, Department of Science, University of Basilicata, Potenza, Italy.
Brigida BochicchioLaboratory of Bioinspired Materials, Department of Science, University of Basilicata, Potenza, Italy.
Andrew SmithSchool of Materials and Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom.
Victoria L WorkmanSchool of Materials and Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom.
Luis A Castillo DiazSchool of Materials and Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom.
Alberto SaianiSchool of Materials and Manchester Institute of Biotechnology, The University of Manchester, Manchester, United Kingdom.
Antonietta PepeLaboratory of Bioinspired Materials, Department of Science, University of Basilicata, Potenza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-assembling peptide hydrogels (SAPHs) represent emerging cell cultures systems in several biomedical applications. The advantages of SAPHs are mainly ascribed to the absence of toxic chemical cross-linkers, the presence of ECM-like fibrillar structures and the possibility to produce hydrogels with a large range of different mechanical properties. We will present a two-component peptide system with tuneable mechanical properties, consisting of a small pentapeptide (SFFSF-NH

Indexed as

HydrogelsMaterials TestingOligopeptidesAnimalsMiceNanofibersNIH 3T3 CellsHydrogelsOligopeptidesatomic force microscopycell cultureelastin sequencehydrogeloscillatory rheologyself-assembling peptides

Identifiers

PMID30456777
PMCPMC6587839

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.