Evidence map›Paper›PMID 30456739›Full record

ArticleSleep & breathing = Schlaf & Atmung2019

Postural and vestibular changes related to CPAP treatment in moderate-to-severe OSA patients: a 12-month longitudinal study.

Marco Alessandrini, Claudio Liguori, Andrea Viziano, Francesca Izzi, Donatella Capoccia, Alessia Lanzillotta, Fabio Placidi, Nicola Biagio Mercuri, Alessandro Micarelli

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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Comments on "Vestibular function in patients diagnosed with obstructive sleep apnea''.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Vestibular function in patients diagnosed with obstructive sleep apnea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Article
  5. Evaluation of vestibular evoked myogenic potentials responses in patients with severe obstructive sleep apnea before and after continuous positive airway pressure therapy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  6. Relationship between sleep apnea and dizziness: a scoping review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Marco AlessandriniDepartment of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Montpellier, 1, E sud Tower, 00133, Rome, Italy.
Claudio LiguoriDepartment of Systems Medicine, Neuroscience Unit, University of Rome Tor Vergata, Rome, Italy.
Andrea VizianoDepartment of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Montpellier, 1, E sud Tower, 00133, Rome, Italy.
Francesca IzziDepartment of Systems Medicine, Neuroscience Unit, University of Rome Tor Vergata, Rome, Italy.
Donatella CapocciaEmergency Department, ASL RM6, Polo H3, Velletri, Italy.
Alessia LanzillottaDepartment of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Montpellier, 1, E sud Tower, 00133, Rome, Italy.
Fabio PlacidiDepartment of Systems Medicine, Neuroscience Unit, University of Rome Tor Vergata, Rome, Italy.
Nicola Biagio MercuriDepartment of Systems Medicine, Neuroscience Unit, University of Rome Tor Vergata, Rome, Italy.
Alessandro MicarelliDepartment of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Montpellier, 1, E sud Tower, 00133, Rome, Italy. alessandromicarelli@yahoo.it.ORCID http://orcid.org/0000-0002-0495-5272
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess whether vestibulo-ocular reflex (VOR) gain, posturography parameters and related clinical outcomes can improve in OSA patients after 12 months of CPAP treatment, taking into consideration that a certain degree of vestibular dysfunction has been identified in these subjects.

methodsVestibular, postural, clinical, and polygraphic parameters were assessed in 32 OSA patients before and after beneficial CPAP treatment by means of video head impulse test (vHIT), static posturography (SP), Dizziness Handicap Inventory (DHI), Epworth Sleepiness Scale (ESS), and Apnea-Hypopnea Index (AHI), respectively, and were compared by means of a "within-subject" ANOVA model and Spearman's rank correlation.

resultsAfter the 12-month period of treatment, OSA patients demonstrated a significant reduction in AHI values, in both opened and closed eyes conditions of surface and length as well as in power spectra recorded in low, middle, and high frequency interval. Although a significant improvement was also recorded among DHI and ESS scores, VOR gain increase did not survive to post-hoc corrections. Finally, positive correlations between the differences between pre- and post-treatment AHI, ESS, and PS values were found.

conclusionsThe present work highlighted that postural instability and dizziness-related conditions due to OSA may improve after 12 months of CPAP treatment. Although VOR gain did not demonstrate significant improvement, this study might open future perspectives directed to assessing VOR gain changes after longer periods of CPAP treatment.

Indexed as

Continuous Positive Airway PressurePostural BalanceReflex, Vestibulo-OcularAdultFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedPolysomnographySleep Apnea, ObstructiveCPAPObstructive sleep apnea syndromePosturographyVestibulo-ocular reflexVideo head impulse test

Identifiers

PMID30456739
OpenAlexW2901471035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.