Evidence map›Paper›PMID 30456495›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Quantitative blood flow evaluation of vasodilation-stress compared with dobutamine-stress in patients with end-stage liver disease using

Jonathan T Abele, Monique Raubenheimer, Vincent G Bain, Greg Wandzilak, Naji AlHulaimi, Richard Coulden, Robert A deKemp, Ran Klein, Randall G Williams, Robert S Warshawski and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Hiding in plain sight: an illustrated pitfall of vasodilator stress testing in patients with liver cirrhosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Cardiac imaging for the assessment of patients being evaluated for liver transplantation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Review
  9. Article
  10. Comparison of myocardial blood flow and flow reserve with dobutamine and dipyridamole stress using rubidium-82 positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  11. Review
  12. Revival of an old stressor: Dobutamine-stimulation for PET myocardial perfusion imaging in patients with end-stage liver disease?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jonathan T AbeleDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada. jabele@ualberta.ca.
Monique RaubenheimerFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Vincent G BainLiver Unit, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Greg WandzilakDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Naji AlHulaimiDivision of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Richard CouldenDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Robert A deKempDivision of Cardiology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Ran KleinDivision of Nuclear Medicine, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Randall G WilliamsDivision of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Robert S WarshawskiDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Lucille D LalondeDivision of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
University of Alberta · CAUniversity of Ottawa · CA

Funding

CIHR MIS-100935
6 · The paper itself

Abstract

backgroundOur aim was to determine if end-stage liver disease (ESLD) is associated with an attenuated response to vasodilator-stress or dobutamine-stress using METHODS AND

resultsPre-liver transplant patients who had a normal dipyridamole-stress (n = 27) or dobutamine-stress (n = 26)

conclusionDipyridamole demonstrates an attenuated vasodilatory response in ESLD patients compared to a non-ESLD control group related to higher resting blood flow and comparatively reduced stress blood flow. Dobutamine does not demonstrate this effect implying it may be the preferred pharmacologic MPI stress agent for ESLD patients.

Indexed as

DobutamineRubidium RadioisotopesVasodilationAdultAgedCoronary CirculationDipyridamoleEnd Stage Liver DiseaseFemaleHumansLiver FailureLiver TransplantationMaleMiddle AgedMyocardial Perfusion ImagingPositron Emission Tomography Computed TomographyDipyridamoleDobutamineRubidium-82Rubidium RadioisotopesVasodilator AgentsCADdobutamineMPImyocardial blood flowPETvasodilators

Identifiers

PMID30456495
OpenAlexW2901042825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.