ArticleLife science alliance2018
Distinctive features of lincRNA gene expression suggest widespread RNA-independent functions.
Article in Life science alliance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
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- Ribozyme-Mediated Knockdown of lncRNA Gene Expression inBio-protocol · 2025Article
- FastTENET: an accelerated TENET algorithm based on manycore computing in Python.Bioinformatics (Oxford, England) · 2024Article
- Robust and heritable knockdown of gene expression using a self-cleaving ribozyme in Drosophila.Genetics · 2024Article
- A mechanistic view of long noncoding RNAs in cancer.Wiley interdisciplinary reviews. RNA · 2022Review
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- Distinct transcription kinetics of pluripotent cell states.Molecular systems biology · 2022Article
- Exploring long non-coding RNA networks from single cell omics data.Computational and structural biotechnology journal · 2022Review
- Association study of a genetic variant in the long intergenic noncoding RNA (linc01080) with schizophrenia in Han Chinese.BMC psychiatry · 2021Article
- Intergenic RNA mainly derives from nascent transcripts of known genes.Genome biology · 2021Article
- Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study.The Lancet. Neurology · 2021Article
- TENET: gene network reconstruction using transfer entropy reveals key regulatory factors from single cell transcriptomic data.Nucleic acids research · 2021Article
- The Contribution of lincRNAs at the Interface between Cell Cycle Regulation and Cell State Maintenance.iScience · 2020Article
- Reverse-genetics studies of lncRNAs-what we have learnt and paths forward.Genome biology · 2020Review
- Interspecies Communication in Holobionts by Non-Coding RNA Exchange.International journal of molecular sciences · 2020Review
- Mammalian RNA Decay Pathways Are Highly Specialized and Widely Linked to Translation.Molecular cell · 2020Article
- Regulation of gene expression by cis-acting long non-coding RNAs.Nature reviews. Genetics · 2020Review
- A genome-wide long noncoding RNA CRISPRi screen identifiesGenome research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eukaryotic genomes produce RNAs lacking protein-coding potential, with enigmatic roles. We integrated three approaches to study large intervening noncoding RNA (lincRNA) gene functions. First, we profiled mouse embryonic stem cells and neural precursor cells at single-cell resolution, revealing lincRNAs expressed in specific cell types, cell subpopulations, or cell cycle stages. Second, we assembled a transcriptome-wide atlas of nuclear lincRNA degradation by identifying targets of the exosome cofactor Mtr4. Third, we developed a reversible depletion system to separate the role of a lincRNA gene from that of its RNA. Our approach distinguished lincRNA loci functioning in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.