Evidence map›Paper›PMID 30456345›Full record

ArticleLife science alliance2018

CHRAC/ACF contribute to the repressive ground state of chromatin.

Alessandro Scacchetti, Laura Brueckner, Dhawal Jain, Tamas Schauer, Xu Zhang, Frank Schnorrer, Bas van Steensel, Tobias Straub, Peter B Becker

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation and Aggregation of Active Module Identification Algorithms.bioRxiv : the preprint server for biology · 2025
    Article
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  13. Long non-coding RNAs: the tentacles of chromatin remodeler complexes.Cellular and molecular life sciences : CMLS · 2021
    Review
  14. IMITATION SWITCH is required for normal chromatin structure and gene repression in PRC2 target domains.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
  16. Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Alessandro ScacchettiMolecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.ORCID https://orcid.org/0000-0002-0254-3717
Laura BruecknerDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2649-1939
Dhawal JainMolecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.
Tamas SchauerMolecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.
Xu ZhangDevelopmental Biology Institute of Marseille, Aix Marseille University, Centre Nationnal de la Recherche Scientifique, Marseille, France.ORCID https://orcid.org/0000-0002-1628-9895
Frank SchnorrerDevelopmental Biology Institute of Marseille, Aix Marseille University, Centre Nationnal de la Recherche Scientifique, Marseille, France.ORCID https://orcid.org/0000-0002-9518-7263
Bas van SteenselDivision of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Tobias StraubBioinformatic Unit, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.ORCID https://orcid.org/0000-0002-0547-0453
Peter B BeckerMolecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilian University Munich, Planegg-Martinsried, Germany.ORCID https://orcid.org/0000-0001-7186-0372
Center for Integrated Protein Science Munich · DEThe Netherlands Cancer Institute · NLAix-Marseille Université · FRFoshan University · CNLudwig-Maximilians-Universität München · DE

Funding

Mapping Technology DevelopmentU54DK107965 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GILBERT, DAVID M · 2015 to 2019
$8.6M
NIDDK NIH HHS U54 DK107965
6 · The paper itself

Abstract

The chromatin remodeling complexes chromatin accessibility complex and ATP-utilizing chromatin assembly and remodeling factor (ACF) combine the ATPase ISWI with the signature subunit ACF1. These enzymes catalyze well-studied nucleosome sliding reactions in vitro, but how their actions affect physiological gene expression remains unclear. Here, we explored the influence of

Identifiers

PMID30456345
PMCPMC6238394
OpenAlexW2768267298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.