Evidence map›Paper›PMID 30455784›Full record

ArticleThe Pan African medical journal2018

Hepatitis B virus infection among sexually active individuals in Nigeria: a cross-sectional study.

Yewande Nejo, Adedayo Omotayo Faneye, Babatunde Olusola, Solomon Bakarey, Adebowale Olayinka, Babatunde Motayo, PERVI Study Group

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yewande NejoDepartment of Biological Sciences, Bowen University Iwo, Nigeria.
Adedayo Omotayo FaneyeDepartment of Virology, College of Medicine University of Ibadan, Nigeria.
Babatunde OlusolaDepartment of Virology, College of Medicine University of Ibadan, Nigeria.
Solomon BakareyDepartment of Virology, College of Medicine University of Ibadan, Nigeria.
Adebowale OlayinkaDepartment of Virology, College of Medicine University of Ibadan, Nigeria.
Babatunde MotayoDepartment of Virology, College of Medicine University of Ibadan, Nigeria.
PERVI Study Group
University of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis B virus (HBV) infection is a major health challenge in sub-Saharan African countries. Chronic HBV infection is a risk factor for severe disease progression. Perinatal and sexual transmissions of Hepatitis B virus are the main routes of infection in HBV endemic countries like Nigeria. However, there is paucity of data as regards the major contributory route of transmission to chronic HBV infection in this region. Also, in Nigeria, not everyone at high risk of the infection has been identified. Therefore our study investigated the prevalence of HBV infection among sexually active individuals in Nigeria.

methodsBlood samples collected from 463 participants (360 sexually active individuals and 103 teenagers) recruited from health institutions across the country were tested for the presence of HBsAg, and HBV nucleic acid related antigen (HBVNRAg) by ELISA. Positive samples were further tested for the presence of HBeAg and antiHBe by ELISA. Data were analyzed using Chi-square and binary logistic regression at p = 0.05.

resultsHBsAg and HBVNRAg were detected in 10.4% and 7.6% of the participants respectively. STI clinic attendees had the highest prevalence for HBsAg (17%; p = 0.002). Teenagers had the lowest HBsAg (1.9; p = 0.002) and HBVNRAg (2.9%; p = 0.0001) prevalence rates. Male gender (p = 0.01) and reproductive age group (p=0.009) were the major predictors of chronic HBV infection.

conclusionSexual transmission was identified as the major contributor to chronic HBV infection. Sexually active individuals especially those with STIs are high risk groups for chronic HBV infection. Interventions targeted at this group is therefore recommended.

Indexed as

AdolescentAdultCross-Sectional StudiesDisease ProgressionFemaleHepatitis B, ChronicHepatitis B e AntigensHepatitis B Surface AntigensHumansMaleMiddle AgedNigeriaPrevalenceRisk FactorsSexual BehaviorSexually Transmitted Diseases, ViralHepatitis B e AntigensHepatitis B Surface Antigenschronic HBV infectionHBV life cycleHepatitis B virus nucleic acid related antigenmale genderoccult infectionSexual transmissionSTI clinic attendees

Identifiers

PMID30455784
PMCPMC6235487
OpenAlexW2809459601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.