Evidence map›Paper›PMID 30455700›Full record

ArticleFrontiers in immunology2018

Limited Foxp3

Cintia L Araujo Furlan, Jimena Tosello Boari, Constanza Rodriguez, Fernando P Canale, Facundo Fiocca Vernengo, Santiago Boccardo, Cristian G Beccaria, Véronique Adoue, Olivier Joffre, Adriana Gruppi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Towards a map of the immune system manipulation network byFrontiers in cellular and infection microbiology · 2025
    Review
  7. Galectin-8 deficiency promotes chronic splenomegaly persistence in Chagas disease.Frontiers in cellular and infection microbiology · 2025
    Article
  8. Article
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  12. Article
  13. Article
  14. Immunosuppression in Malaria: DoPathogens (Basel, Switzerland) · 2021
    Review
  15. Review
  16. CD8Frontiers in cellular and infection microbiology · 2021
    Article
  17. The Blockade of Interleukin-2 During the Acute Phase ofFrontiers in cellular and infection microbiology · 2021
    Article
  18. Article
  19. Understanding CD8Trends in parasitology · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Cintia L Araujo FurlanDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Jimena Tosello BoariDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Constanza RodriguezDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Fernando P CanaleDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Facundo Fiocca VernengoDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Santiago BoccardoDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Cristian G BeccariaDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Véronique AdoueInstitut National de la Santé et de la Recherche Médicale, Toulouse, France.
Olivier JoffreInstitut National de la Santé et de la Recherche Médicale, Toulouse, France.
Adriana GruppiDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Carolina L MontesDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Eva V Acosta RodriguezDepartamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Research Centre in Biological Chemistry of Córdoba · ARCentre de Physiopathologie de Toulouse-Purpan · FRConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nacional de Córdoba · AR

Funding

IL-17RA-signaling cytokines in the regulation of CD8 T cell immunity to T. cruziR01AI110340 · NIAID · NATIONAL RESEARCH COUNCIL OF ARGENTINA · PI ACOSTA RODRIGUEZ, EVA V · 2014 to 2018
$667k
NIAID NIH HHS R01 AI110340
6 · The paper itself

Abstract

While it is now acknowledged that CD4

Indexed as

Adoptive TransferAnimalsCD8-Positive T-LymphocytesCell ProliferationChagas DiseaseLymphocyte ActivationMice, Inbred BALB CMice, Inbred C57BLT-Lymphocytes, RegulatoryTrypanosoma cruziCD8 cytotoxic T cells+immunitypathogenesisregulatory T (Treg) cellsTrypanosoma cruzi

Identifiers

PMID30455700
PMCPMC6230662
OpenAlexW2899809138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.