Evidence map›Paper›PMID 30455685›Full record

ArticleFrontiers in immunology2018

The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes.

Yoelys Cruz-Leal, Daniel Grubaugh, Catarina V Nogueira, Isbel Lopetegui-González, Anaixis Del Valle, Felipe Escalona, Rady J Laborde, Carlos Alvarez, Luis E Fernández, Michael N Starnbach and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Antigen Cross-Presentation by Macrophages.Frontiers in immunology · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Yoelys Cruz-LealLaboratory of Toxins and Liposomes, Center for Protein Studies, Faculty of Biology, University of Havana, Havana, Cuba.
Daniel GrubaughDepartment of Microbiology and Immunobiology of Harvard Medical School, Harvard University, Boston, MA, United States.
Catarina V NogueiraDepartment of Microbiology and Immunobiology of Harvard Medical School, Harvard University, Boston, MA, United States.
Isbel Lopetegui-GonzálezDepartment of Biochemistry, Faculty of Biology, University of Havana, Havana, Cuba.
Anaixis Del ValleDepartment of Biochemistry, Faculty of Biology, University of Havana, Havana, Cuba.
Felipe EscalonaLaboratory of Toxins and Liposomes, Center for Protein Studies, Faculty of Biology, University of Havana, Havana, Cuba.
Rady J LabordeDepartment of Biochemistry, Faculty of Biology, University of Havana, Havana, Cuba.
Carlos AlvarezLaboratory of Toxins and Liposomes, Center for Protein Studies, Faculty of Biology, University of Havana, Havana, Cuba.
Luis E FernándezImmunobiology Direction, Center of Molecular Immunology, Havana, Cuba.
Michael N StarnbachDepartment of Microbiology and Immunobiology of Harvard Medical School, Harvard University, Boston, MA, United States.
Darren E HigginsDepartment of Microbiology and Immunobiology of Harvard Medical School, Harvard University, Boston, MA, United States.
María E LanioLaboratory of Toxins and Liposomes, Center for Protein Studies, Faculty of Biology, University of Havana, Havana, Cuba.
University of Havana · CUHarvard University · USCenter of Molecular Immunology (Cuba) · CU

Funding

Cytotoxic T Cell Mediated Immunity to ChlamydiaR01AI039558 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI STARNBACH, MICHAEL N · 2001 to 2025
$15.6M
NIAID NIH HHS R01 AI039558
6 · The paper itself

Abstract

Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8

Indexed as

AnimalsAntigensCD8 AntigensCells, CulturedCnidarian VenomsCross-PrimingDendritic CellsFemaleLeupeptinsLiposomesLymphocyte ActivationMacrophagesMiceMice, Inbred C57BLOvalbuminT-Lymphocytes, CytotoxicAntigensCD8 AntigensCnidarian VenomsleupeptinLeupeptinsLiposomesOvalbuminsticholysin IIantigen cross-presentationcytotoxic immune responsedendritic cellsliposomesmacrophagespore-forming proteinsticholysin II

Identifiers

PMID30455685
PMCPMC6230584
OpenAlexW2900009009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.