Evidence map›Paper›PMID 30455625›Full record

ArticleFrontiers in neuroscience2018

Altered Intracortical T

Christopher D Rowley, Sarah J Tabrizi, Rachael I Scahill, Blair R Leavitt, Raymund A C Roos, Alexandra Durr, Nicholas A Bock

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Christopher D RowleyMcMaster Integrative Neuroscience Discovery and Study Program, McMaster University, Hamilton, ON, Canada.
Sarah J TabriziHuntington's Disease Centre, University College London Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.
Rachael I ScahillHuntington's Disease Centre, University College London Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.
Blair R LeavittDepartment of Medical Genetics, The University of British Columbia, Vancouver, BC, Canada.
Raymund A C RoosDepartment of Neurology, Leiden University Medical Center, Leiden, Netherlands.
Alexandra DurrINSERM U1127, CNRS UMR7225, UMR_S1127, UPMC Université Paris VI, Institut du Cerveau et de la Moelle Epinière, Sorbonne University, Paris, France.
Nicholas A BockDepartment of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.
McMaster University · CAInserm · FRLeiden University Medical Center · NLNational Hospital for Neurology and Neurosurgery · GBUniversity College London · GBUniversity of British Columbia · CA

Funding

Wellcome Trust 200181/Z/15/Z
6 · The paper itself

Abstract

Huntington's disease (HD) is a genetic neurodegenerative disorder that is characterized by neuronal cell death. Although medium spiny neurons in the striatum are predominantly affected, other brain regions including the cerebral cortex also degenerate. Previous structural imaging studies have reported decreases in cortical thickness in HD. Here we aimed to further investigate changes in cortical tissue composition

Indexed as

cerebral cortexHuntington’s diseaseMRImyelinneurodegeneration

Identifiers

PMID30455625
PMCPMC6230564
OpenAlexW2899869201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.