ArticlePediatrics2018
The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States.
Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06261554 (Efficacy and Safety of Low-dose Sesame Oral Immunotherapy in Pediatric Patients), which is not on this map. Cited by 385 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Low-dose Sesame Oral Immunotherapy in Pediatric Patients: A Randomized Controlled Trial
Who cites it
385 citing papers in PubMed, 5 syntheses or guidelines pooled it, 836 citations in OpenAlex.
- Dietary Management of IgE-Mediated and Non-IgE-Mediated Food Allergies: A Systematic Review of Current Evidence and Clinical Implications.Nutrients · 2026Pooled it
- Prenatal n-3 LC-PUFA intake and the incidence of allergic diseases in offspring: an updated systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Nutrition and Gut Microbiome in the Prevention of Food Allergy.Nutrients · 2025Pooled it
- Guideline
- Prevalence of shrimp allergy: a meta-analysis based on different diagnostic methods.Frontiers in allergy · 2025Pooled it
- Early-life peanut oral immunotherapy associated with long-term ingestion and immunologic changes.The Journal of allergy and clinical immunology · 2026Trial
- Assessing pediatric clinician adherence to the guidelines for prevention of peanut allergy: a natural language processing study.BMC medical informatics and decision making · 2025Trial
- Transepidermal Water Loss in Oral Food Challenges in Children With Peanut Allergy: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Pediatric Clinician Adherence to Peanut Allergy Prevention Guidelines: A Randomized Trial.Pediatrics · 2025Trial
- Incidence of food allergic reactions among adolescents engaged in food allergy management.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Trial
- HLA-DRAllergy · 2025Trial
- Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy.Allergy · 2025Trial
- Efficacy and Safety of Dupilumab in Children With Peanut Allergy: A Multicenter, Open-Label, Phase II Study.Allergy · 2025Trial
- Omalizumab for the Treatment of Multiple Food Allergies.The New England journal of medicine · 2024Trial
- Trial
- Specialized Nutrition Products in Pediatric Medical Care: Clinical Applications, Formulation, Regulation, and Future Directions.Nutrients · 2026Review
- Geospatial and insurance barriers to allergist access across the Midwest.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026Article
- Recent Updates in the Management of Anaphylaxis: The Role of the Pediatrician.Journal of pediatrics. Clinical practice · 2026Article
- Early-Life Nutrition: The Interplay of Nutritional, Microbial, Genetic, and Environmental Factors in Food Allergy Development and Prevention.Nutrients · 2026Review
- Article
325 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
: media-1vid110.1542/5840360268001PEDS-VA_2018-1235
methodsA survey was administered to US households between 2015 and 2016, obtaining parent-proxy responses for 38 408 children. Prevalence estimates were based on responses from NORC at the University of Chicago's nationally representative, probability-based AmeriSpeak Panel (51% completion rate), which were augmented by nonprobability-based responses via calibration weighting to increase precision. Prevalence was estimated via weighted proportions. Multiple logistic regression models were used to evaluate FA predictors.
resultsOverall, estimated current FA prevalence was 7.6% (95% confidence interval: 7.1%-8.1%) after excluding 4% of children whose parent-reported FA reaction history was inconsistent with immunoglobulin E-mediated FA. The most prevalent allergens were peanut (2.2%), milk (1.9%), shellfish (1.3%), and tree nut (1.2%). Among food-allergic children, 42.3% reported ≥1 severe FA and 39.9% reported multiple FA. Furthermore, 19.0% reported ≥1 FA-related emergency department visit in the previous year and 42.0% reported ≥1 lifetime FA-related emergency department visit, whereas 40.7% had a current epinephrine autoinjector prescription. Prevalence rates were higher among African American children and children with atopic comorbidities.
conclusionsFA is a major public health concern, affecting ∼8% of US children. However, >11% of children were perceived as food-allergic, suggesting that the perceived disease burden may be greater than previously acknowledged.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.