ArticleProceedings of the National Academy of Sciences of the United States of America2018
Artemisinin resistance phenotypes and K13 inheritance in a
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
What it found
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Who cites it
39 citing papers in PubMed, 54 citations in OpenAlex.
- Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.PLoS medicine · 2020Trial
- Paclitaxel-induced tubulin dysfunction stalls parasite development: synergistic potential with artemisinin against resistant strains.Microbiology spectrum · 2026Article
- LL-37 selectively targets Plasmodium-infected erythrocytes and exhibits antimalarial activity.PLoS pathogens · 2026Article
- Epigenetically conferred ring-stage survival in Plasmodium falciparum against artemisinin treatment.Nature communications · 2025Article
- Isolation and characterization ofAntimicrobial agents and chemotherapy · 2025Article
- Assessing fitness costs in malaria parasites: a comprehensive review and implications for drug resistance management.Malaria journal · 2025Review
- Article
- Progressive heterogeneity of enlarged and irregularly shaped apicoplasts inbioRxiv : the preprint server for biology · 2024Article
- An overview of artemisinin-resistant malaria and associated Pfk13 gene mutations in Central Africa.Parasitology research · 2024Review
- The human malaria-Antimicrobial agents and chemotherapy · 2024Review
- Combating antimicrobial resistance in malaria, HIV and tuberculosis.Nature reviews. Drug discovery · 2024Review
- Malaria Control by Mass Drug Administration With Artemisinin Plus Piperaquine on Grande Comore Island, Union of Comoros.Open forum infectious diseases · 2023Article
- A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses.Antimicrobial agents and chemotherapy · 2023Article
- Article
- Current status of experimental models for the study of malaria.Parasitology · 2022Review
- Artemisinin resistance and malaria elimination: Where are we now?Frontiers in pharmacology · 2022Review
- Toward New Transmission-Blocking Combination Therapies: Pharmacokinetics of 10-Amino-Artemisinins and 11-Aza-Artemisinin and Comparison with Dihydroartemisinin and Artemether.Antimicrobial agents and chemotherapy · 2021Article
- Article
- The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice.Communications biology · 2021Article
- Genomic and Genetic Approaches to Studying Antimalarial Drug Resistance and Plasmodium Biology.Trends in parasitology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
46 authors at 4 institutions in 1 country.
Juliana M SáLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Sarah R KaslowLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Michael A KrauseLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Viviana A Melendez-MunizLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Rebecca E SalzmanLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Whitney A KiteLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Min ZhangCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL 33612.
Roberto R Moraes BarrosLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Jianbing MuLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Paul K HanLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
J Patrick MershonLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Christine E FiganLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Ramoncito L CaleonLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Rifat S RahmanLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Tyler J GibsonLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Chanaki AmaratungaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Erika P NishiguchiLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Kimberly F BreglioLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Theresa M EngelsDivision of Veterinary Research, Office of Research Services, National Institutes of Health, Bethesda, MD 20892.
Soundarapandian VelmuruganSanaria, Rockville, MD 20850.
Stacy RicklefsResearch Technology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Judith StraimerDepartment of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Nina F GnädigDepartment of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Bingbing DengLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Anna LiuLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Ababacar DioufLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Kazutoyo MiuraLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Gregory S TulloLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Richard T EastmanLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Sumana ChakravartySanaria, Rockville, MD 20850.
Eric R JamesSanaria, Rockville, MD 20850.
Kenneth UdenzeCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL 33612.
Suzanne LiCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL 33612.
Daniel E SturdevantResearch Technology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Robert W GwadzLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Stephen F PorcellaResearch Technology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.
Carole A LongLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
David A FidockDepartment of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Marvin L ThomasDivision of Veterinary Research, Office of Research Services, National Institutes of Health, Bethesda, MD 20892.
Michael P FayBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
B Kim Lee SimSanaria, Rockville, MD 20850.
Stephen L HoffmanSanaria, Rockville, MD 20850.
John H AdamsCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL 33612.
Rick M FairhurstLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Xin-Zhuan SuLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Thomas E WellemsLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; twellems@niaid.nih.gov.ORCID 0000-0003-3899-8454
National Institutes of Health · USSanaria · USUniversity of South Florida · USColumbia University · US
Funding
Malaria Drug Resistance and Disease VirulenceZIAAI000483 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI WELLEMS, THOMAS E · 2009 to 2025
$24.5MMalaria Parasite Sexual Development, Drug Resistance, and EvolutionZIAAI000892 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, XINZHUAN · 2009 to 2025
$23.3MChemogenomic Profiling of Plasmodium Falciparum Responses and ResistanceR01AI117017 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2015 to 2025
$6.9MDefining P. falciparum resistance to artemisinin-based combination therapiesR01AI109023 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FIDOCK, DAVID A · 2014 to 2025
$4.4MDiscovering the essential genome of Plasmodium falciparumR01AI130171 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2018 to 2021
$2.8MA large-scale transposon mutagenesis screen of Plasmodium falciparumR01AI094973 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2011 to 2015
$1.8MIntramural NIH HHS ZIA AI000483NIAID NIH HHS R01 AI094973NIAID NIH HHS R01 AI109023NIAID NIH HHS R01 AI117017NIAID NIH HHS R01 AI130171
Abstract
Concerns about malaria parasite resistance to treatment with artemisinin drugs (ARTs) have grown with findings of prolonged parasite clearance
Indexed as
AnimalsAntimalarialsAotidaeArtemisininsCrosses, GeneticDrug ResistanceGene Expression RegulationMalaria, FalciparumMutationPlasmodium falciparumProtozoan ProteinsAntimalarialsartemisininArtemisininsProtozoan Proteinsartemisinin-based combination chemotherapygenetic crossmalariaparasite clearance timerecrudescence
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.