Evidence map›Paper›PMID 30455232›Full record

ArticleAntimicrobial agents and chemotherapy2019

Evaluation of Carbapenems for Treatment of Multi- and Extensively Drug-Resistant

Sander P van Rijn, Marlanka A Zuur, Richard Anthony, Bob Wilffert, Richard van Altena, Onno W Akkerman, Wiel C M de Lange, Tjip S van der Werf, Jos G W Kosterink, Jan-Willem C Alffenaar

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Non-canonical peptidoglycan cross-linking is essential forbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Toward better cures forClinical microbiology reviews · 2024
    Review
  4. ISCCM Position Statement on the Approach to and Management of Critically Ill Patients with Tuberculosis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Are the Newer Carbapenems of Any Value against Tuberculosis.Antibiotics (Basel, Switzerland) · 2022
    Article
  11. Anti-tuberculosis drug developmentFrontiers in microbiology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Pharmacologic management ofExpert review of clinical pharmacology · 2020
    Review
  17. Review
  18. Article
  19. Tuberculosis parenteral therapeutic regimens for critical patients or non-functional intestinal tract: Brief review and proposal of protocol.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sander P van Rijn *University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands.
Marlanka A Zuur *University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands.
Richard AnthonyNational Institute for Public Health and the Environment, National Mycobacteria Reference Laboratory, Bilthoven, The Netherlands.
Bob WilffertUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands.
Richard van AltenaUniversity of Groningen, University Medical Center Groningen, Tuberculosis Centre Beatrixoord, Haren, The Netherlands.
Onno W AkkermanUniversity of Groningen, University Medical Center Groningen, Tuberculosis Centre Beatrixoord, Haren, The Netherlands.
Wiel C M de LangeUniversity of Groningen, University Medical Center Groningen, Tuberculosis Centre Beatrixoord, Haren, The Netherlands.
Tjip S van der WerfUniversity of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands.
Jos G W KosterinkUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands.
Jan-Willem C AlffenaarUniversity of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands j.w.c.alffenaar@umcg.nl.
University of Groningen · NLUniversity Medical Center Groningen · NLNational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi- and extensively drug-resistant tuberculosis (M/XDR-TB) has become an increasing threat not only in countries where the TB burden is high but also in affluent regions, due to increased international travel and globalization. Carbapenems are earmarked as potentially active drugs for the treatment of

Indexed as

AnimalsCarbapenemsErtapenemExtensively Drug-Resistant TuberculosisFemaleImipenemMeropenemMiceMice, Inbred BALB CMice, Inbred C57BLMycobacterium tuberculosisProspective StudiesCarbapenemsErtapenemImipenemMeropenemcarbapenemsclinicalertapenemimipenemin vitroin vivomeropenemtuberculosis

Identifiers

PMID30455232
PMCPMC6355583
OpenAlexW2921036699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.