ArticleInfection and immunity2019
Novel Assay To Characterize Neutrophil Responses to Oral Biofilms.
Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Prognostic utility of oral neutrophil counts in high-risk periodontitis: A retrospective study.Journal of periodontology · 2025Article
- Correlation Between Periodontal Disease and Oral, Oropharyngeal, and Parapharyngeal Cancers.Clinical, cosmetic and investigational dentistry · 2025Article
- Bidirectional effects of neutrophils onJournal of oral microbiology · 2025Article
- Extracellular host DNA contributes to pathogenic biofilm formation during periodontitis.Frontiers in cellular and infection microbiology · 2024Article
- Discovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Review
- Multiparametric Profiling of Neutrophil Function via a High-Throughput Flow Cytometry-Based Assay.Cells · 2023Article
- Article
- The Effect of Intensity-Modulated Radiotherapy to the Head and Neck Region on the Oral Innate Immune Response and Oral Microbiome: A Prospective Cohort Study of Head and Neck Tumour Patients.International journal of molecular sciences · 2022Article
- Metronidazole enhances killing ofFrontiers in oral health · 2022Article
- PAMPs and DAMPs as the Bridge Between Periodontitis and Atherosclerosis: The Potential Therapeutic Targets.Frontiers in cell and developmental biology · 2022Review
- Review
- Neutrophils exhibit an individual response to different oral bacterial biofilms.Journal of oral microbiology · 2020Article
- The Crossroads of Periodontitis and Oral Squamous Cell Carcinoma: Immune Implications and Tumor Promoting Capacities.Frontiers in oral health · 2020Review
- Oral Neutrophils: Underestimated Players in Oral Cancer.Frontiers in immunology · 2020Review
- The Neutrophil: Constant Defender and First Responder.Frontiers in immunology · 2020Review
- Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?Frontiers in bioengineering and biotechnology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neutrophils, the most numerous leukocytes, play an important role in maintaining oral health through interactions with oral microbial biofilms. Both neutrophil hyperactivity and the bacterial subversion of neutrophil responses can cause inflammation-mediated tissue damage like that seen in periodontal disease. We describe here an assay that assesses neutrophil activation responses to monospecies biofilm bacteria
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.