ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Computing Value from Quality and Quantity in Human Decision-Making.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Distinct contributions of prefrontal, parietal, and cingulate signals to exploratory decisions.Communications biology · 2026Article
- Abnormal topological organization of functional brain networks in the patients with anterior segment ischemic optic neuropathy.Frontiers in neuroscience · 2024Article
- Anterior cingulate and medial prefrontal cortex oscillations underlie learning alterations in trait anxiety in humans.Communications biology · 2023Article
- The neural correlates of value representation: From single items to bundles.Human brain mapping · 2023Article
- Dynamic computation of value signals via a common neural network in multi-attribute decision-making.Social cognitive and affective neuroscience · 2022Article
- Neuroprotection in late life attention-deficit/hyperactivity disorder: A review of pharmacotherapy and phenotype across the lifespan.Frontiers in human neuroscience · 2022Review
- The Computational and Neural Substrates of Ambiguity Avoidance in Anxiety.Computational psychiatry (Cambridge, Mass.) · 2022Article
- Single-Dimensional Human Brain Signals for Two-Dimensional Economic Choice Options.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Excitatory-inhibitory tone shapes decision strategies in a hierarchical neural network model of multi-attribute choice.PLoS computational biology · 2021Article
- Altered Brain Functional Connectivity at Resting-State in Patients With Non-arteritic Anterior Ischemic Optic Neuropathy.Frontiers in neuroscience · 2021Article
- A Critical Role for Human Ventromedial Frontal Lobe in Value Comparison of Complex Objects Based on Attribute Configuration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
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Authors and funding
5 authors.
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Abstract
How organisms learn the value of single stimuli through experience is well described. In many decisions, however, value estimates are computed "on the fly" by combining multiple stimulus attributes. The neural basis of this computation is poorly understood. Here we explore a common scenario in which decision-makers must combine information about quality and quantity to determine the best option. Using fMRI, we examined the neural representation of quality, quantity, and their integration into an integrated subjective value signal in humans of both genders. We found that activity within inferior frontal gyrus (IFG) correlated with offer quality, while activity in the intraparietal sulcus (IPS) specifically correlated with offer quantity. Several brain regions, including the anterior cingulate cortex (ACC), were sensitive to an interaction of quality and quantity. However, the ACC was uniquely activated by quality, quantity, and their interaction, suggesting that this region provides a substrate for flexible computation of value from both quality and quantity. Furthermore, ACC signals across subjects correlated with the strength of quality and quantity signals in IFG and IPS, respectively. ACC tracking of subjective value also correlated with choice predictability. Finally, activity in the ACC was elevated for choice trials, suggesting that ACC provides a nexus for the computation of subjective value in multiattribute decision-making.
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