Evidence map›Paper›PMID 30454860›Full record

ArticleAllergologia et immunopathologia

Evidence for respiratory viruses interactions in asymptomatic preschool-aged children.

K Douros, D Kotzia, C Kottaridi, A Giotas, B Boutopoulou, E Bozas, V Matziou, K Priftis, V Papaevangelou

Open access · diamondAbstract read
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Article in Allergologia et immunopathologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

K DourosThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: costasdouros@gmail.com.
D KotziaThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
C KottaridiDepartment of Cytopathology, University General Hospital "Attikon", University of Athens School of Medicine, Athens, Greece.
A GiotasThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
B BoutopoulouThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
E BozasFaculty of Nursing, National and Kapodestrian University of Athens, Athens, Greece.
V MatziouFaculty of Nursing, National and Kapodestrian University of Athens, Athens, Greece.
K PriftisThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
V PapaevangelouThird Department of Pediatrics, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo prospectively evaluate interferences between viruses of the upper respiratory tract in asymptomatic preschool children.

methodsNasal-pharyngeal swabs from 233 preschool aged children were prospectively collected over four consecutive time periods, during one school year. The samples were tested using a RT-PCR DNA/RNA microarray system for nine respiratory viruses.

resultsRespiratory syncytial virus (RSV) was a predictor of the presence of influenza virus (INFL) (OR: 9.12, CI: 1.52-54.75, p=0.016), and similarly, INFL predicted the presence of RSV (OR: 4.01, CI: 1.14-14.16, p=0.030). Also, rhinovirus (RV) was a predictor of adenovirus (ADV) presence (OR: 3.66, CI: 1.10-12.14, p=0.034), and similarly, ADV predicted the presence of RV (OR: 4.05, CI: 1.02-16.05, p=0.046). No other significant associations between viruses were observed.

conclusionOur results indicate that respiratory viruses found in carrier stage in asymptomatic children may interact with other viruses and even facilitate their settling in the upper respiratory tract. The pathophysiological role of these interactions is not yet clear.

Indexed as

AdenoviridaeAdenoviridae InfectionsAsymptomatic DiseasesChild, PreschoolCommon ColdFemaleGreeceHumansInfluenza, HumanMaleOrthomyxoviridaePrognosisProspective StudiesRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsChildrenInteractionsRespiratory viruses

Identifiers

PMID30454860
PMCPMC7126143
OpenAlexW2901356734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.