Evidence map›Paper›PMID 30454732›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2018

Predictors of Complications in Anorexia Nervosa and Atypical Anorexia Nervosa: Degree of Underweight or Extent and Recency of Weight Loss?

Melissa Whitelaw, Katherine J Lee, Heather Gilbertson, Susan M Sawyer

Abstract read
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In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Momentary physiological indices related to eating disorders: A systematic and methodological review.European eating disorders review : the journal of the Eating Disorders Association · 2024
    Pooled it
  2. Medical Management of Restrictive Eating Disorders in Adolescents and Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Guideline
  3. Pooled it
  4. Trial
  5. Renal Function in Patients Hospitalized With Anorexia Nervosa Undergoing Refeeding: Findings From the Study of Refeeding to Optimize Inpatient Gains.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Do Weight Suppression and Body Mass Index Predict Daily Body Image and Eating Urges in Non-Clinical Adults?European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Impairments in personality functioning in adolescents with anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Melissa WhitelawDepartment of Nutrition and Food Services, The Royal Children's Hospital, Melbourne, Australia; Department of Adolescent Medicine, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Murdoch Children's Research Institute, Melbourne, Australia. Electronic address: melissa.whitelaw@rch.org.au.
Katherine J LeeDepartment of Paediatrics, The University of Melbourne, Melbourne, Australia; Murdoch Children's Research Institute, Melbourne, Australia.
Heather GilbertsonDepartment of Nutrition and Food Services, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Murdoch Children's Research Institute, Melbourne, Australia.
Susan M SawyerDepartment of Adolescent Medicine, The Royal Children's Hospital, Melbourne, Australia; Centre for Adolescent Health, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Murdoch Children's Research Institute, Melbourne, Australia.
Royal Children's Hospital · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdolescents with atypical anorexia nervosa (AAN) can experience severe physical complications despite not being underweight, posing questions about the contribution of weight loss to complications experienced in restrictive eating disorders (EDs). This study compared total weight loss and recent weight loss with admission weight as predictors of physical and psychological complications.

methodsRetrospective (2005-2010) and prospective (2011-2013) studies were undertaken of 12- to 19-year-old hospitalized adolescents with anorexia nervosa (AN) or AAN, defined as meeting criteria for AN except underweight (≥85% median body mass index). Predictors were total weight loss (from lifetime maximum), recent weight loss (past 3 months), and admission weight. Outcomes were hypophosphatemia, clinical, anthropometric, and psychometric markers during admission.

resultsIn 171 participants (AN, 118 [69%]; AAN, 53 [31%]), there was little evidence of an association between weight measures and hypophosphatemia. Greater total weight loss (regression coefficient [Coeff]: -1.70, 95% confidence interval [CI]: -2.77, -.63, p = .002) and greater recent weight loss (Coeff: -3.37, 95% CI: -5.77, -.97, p = .006), but not admission weight, were associated with a lower pulse rate nadir. Greater total weight loss (odds ratio [OR]: 1.70, 95% CI: 1.19, 2.24, p = .003) and greater recent weight loss (OR: 2.12, 95% CI: 1.11, 4.02, p = .02) were also associated with a higher incidence of bradycardia.

conclusionsIn adolescents with restrictive EDs, total weight loss and recent weight loss were better predictors than admission weight of many physical complications. This suggests that future diagnostic criteria for AN place greater emphasis on weight loss.

Indexed as

Anorexia NervosaAdolescentBody Mass IndexBody WeightChildFemaleHospitalizationHumansHypophosphatemiaMaleProspective StudiesRetrospective StudiesWeight LossAnorexia nervosaAtypical anorexia nervosaBradycardiaHypophosphatemiaStarvationWeight loss

Identifiers

PMID30454732
OpenAlexW2900799578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.