Evidence map›Paper›PMID 30454065›Full record

ArticleBMC research notes2018

The influence of maternal pregnancy glucose concentrations on associations between a fetal imprinted gene allele score and offspring size at birth.

Clive J Petry, Ken K Ong, Ieuan A Hughes, Carlo L Acerini, David B Dunger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clive J PetryDepartment of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Hills Road, Box 116, Cambridge, CB2 0QQ, UK. cjp1002@cam.ac.uk.ORCID http://orcid.org/0000-0002-6642-9825
Ken K OngDepartment of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Hills Road, Box 116, Cambridge, CB2 0QQ, UK.
Ieuan A HughesDepartment of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Hills Road, Box 116, Cambridge, CB2 0QQ, UK.
Carlo L AceriniDepartment of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Hills Road, Box 116, Cambridge, CB2 0QQ, UK.
David B DungerDepartment of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Hills Road, Box 116, Cambridge, CB2 0QQ, UK.
University of Cambridge · GBMRC Laboratory of Molecular Biology · GB

Funding

Diabetes UK 11/0004241Evelyn Trust EW9035322Fifth Framework Programme QLK4-1999-01422Medical Research Council 7500001180Medical Research Council G1001995Medical Research Council MC_UU_12015/2Mothercare Charitable Foundation (GB) RG54608Newlife Foundation for Disabled Children 07/20Wellbeing of Women RG1644Wellcome Trustworld cancer research fund international (gb) 2004/03
6 · The paper itself

Abstract

objectivePreviously we found that certain fetal imprinted genes represented as an allele score are associated with maternal pregnancy glucose concentrations. Recently it was reported that fetal polymorphisms with strong associations with birth weight tend to mediate these independently of increases in maternal pregnancy glucose concentrations. We therefore investigated whether potential associations between the fetal allele score and birth weight were related to maternal glucose concentrations in the Cambridge Baby Growth Study.

resultsThe fetal imprinted gene allele score was positively associated with birth weight (β = 63 (17-109) g/risk allele, β' = 0.113, p = 7.6 × 10

Indexed as

AllelesBirth WeightGenomic ImprintingMothersPolymorphism, GeneticAdultBlood GlucoseFemaleGenotypeGestational AgeHematologic TestsHumansInfant, NewbornInfant, Small for Gestational AgeLongitudinal StudiesMaleBlood GlucoseCohort studyDevelopmentGestational diabetesGrowthPregnancy

Identifiers

PMID30454065
PMCPMC6245772
OpenAlexW2900867452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.