ArticleJournal of translational medicine2018
Associations of immunological factors with metabolic syndrome and its characteristic elements in Chinese centenarians.
Article in Journal of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
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- C-Reactive Protein, Neutrophil-to-Lymphocyte Ratio, and Long-Term Mortality in Chinese Centenarians.JAMA network open · 2023Article
- Associations between lipid profiles and late-life cognitive impairment among oldest-old and centenarian adults.MedComm · 2023Article
- Positive associations between sex hormones, bone metabolism and cognitive impairment in Chinese oldest-old females.BMC psychiatry · 2023Article
- The Complement System, Aging, and Aging-Related Diseases.International journal of molecular sciences · 2022Review
- Malnutrition is positively associated with cognitive decline in centenarians and oldest-old adults: A cross-sectional study.EClinicalMedicine · 2022Article
- Cross-sectional analysis of gonadal hormone expression and relevant factors in female centenarians in Hainan, China.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Roles for c-Abl in postoperative neurodegeneration.International journal of medical sciences · 2022Review
- Age Related Cognitive Function Was Positively Associated with Diastolic Pressure and Negatively Associated with Antibody Expression in Chinese Oldest-Old and Centenarian Adults.Journal of inflammation research · 2022Article
- Relationships Between Traditional Chinese Medicine Constitution and Age-Related Cognitive Decline in Chinese Centenarians.Frontiers in aging neuroscience · 2022Article
- How Should Anesthesiologists Face Coronavirus Disease 2019?Frontiers in cardiovascular medicine · 2022Review
- Preoperative malnutrition as an independent risk factor for the postoperative mortality in elderly Chinese individuals undergoing hip surgery: a single-center observational study.Therapeutic advances in chronic disease · 2022Article
- Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults.Therapeutic advances in chronic disease · 2022Article
- Centenarian longevity had inverse relationships with nutritional status and abdominal obesity and positive relationships with sex hormones and bone turnover in the oldest females.Journal of translational medicine · 2021Article
- Associations Between Complement Components and Vitamin D and the Physical Activities of Daily Living Among a Longevous Population in Hainan, China.Frontiers in immunology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMetabolic syndrome (MetS) has an increased prevalence (approximately 20-25% of the adult population) all over the world. Immunological function is significantly associated with the development of MetS, and MetS is beginning to be considered as a chronic immune-related disease. The present study addressed on the associations of immunological factors with MetS and its characteristic elements in Chinese centenarians.
methodsHainan is a longevity region with the highest population density of centenarians in China. The China Hainan Centenarian Cohort Study has a considerable sample size, and provides a significant population-based sample of centenarians. Home interview, physical examination and blood analysis were conducted following standard procedures.
resultsAll centenarians had a median age of 102 (100-115) years, and the proportion of females was 80.8%. The proportion of centenarians with MetS was 16.0% (135 centenarians). Abdominal obesity, hypertension, dyslipidemia and diabetes mellitus had a prevalence of 26.4% (223 centenarians), 73.7% (623 centenarians), 40.4% (341 centenarians) and 10.7% (90 centenarians), respectively. In Logistic regression analyses, MetS was significantly associated with immunoglobulin E and complement C3 levels (P < 0.05 for all). Abdominal obesity was significantly associated with immunoglobulin E and complement C3 levels (P < 0.05 for all).
conclusionsThe present study provides epidemiological evidence that MetS has significant associations with immunoglobulin E and complement C3 levels, and demonstrates that abdominal obesity is significantly associated with immunoglobulin E and complement C3 levels in Chinese centenarians.
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